Lin R - Search Results

1

Degradation of Hexokinase 2 Blocks Glycolysis and Induces GSDME-Dependent Pyroptosis to Amplify Immunogenic Cell Death for Breast Cancer Therapy.

Sang R, Fan R, Deng A, Gou J, Lin R, Zhao T, Hai Y, Song J, Liu Y, Qi B, Du G, Cheng M, Wei G. Sang R, et al. Among authors: lin r. J Med Chem. 2023 Jul 13;66(13):8464-8483. doi: 10.1021/acs.jmedchem.3c00118. Epub 2023 Jun 27. J Med Chem. 2023. PMID: 37376788

2

CJ₂: A Novel Potent Platinum(IV) Prodrug Enhances Chemo-Immunotherapy by Facilitating PD-L1 Degradation in the Cytoplasm and Cytomembrane.

Fan R, Deng A, Qi B, Zhang S, Sang R, Luo L, Gou J, Liu Y, Lin R, Zhao M, Liu Y, Yang L, Cheng M, Wei G. Fan R, et al. Among authors: lin r. J Med Chem. 2023 Jan 12;66(1):875-889. doi: 10.1021/acs.jmedchem.2c01719. Epub 2023 Jan 3. J Med Chem. 2023. PMID: 36594812

3

A novel mitochondria-targeting DHODH inhibitor induces robust ferroptosis and alleviates immune suppression.

Hai Y, Fan R, Zhao T, Lin R, Zhuang J, Deng A, Meng S, Hou Z, Wei G. Hai Y, et al. Among authors: lin r. Pharmacol Res. 2024 Apr;202:107115. doi: 10.1016/j.phrs.2024.107115. Epub 2024 Feb 27. Pharmacol Res. 2024. PMID: 38423231 Free article.

4

Novel Pt(IV) complex OAP2 induces STING activation and pyroptosis via mitochondrial membrane remodeling for synergistic chemo-immunotherapy.

Fan R, Lin R, Zhang S, Deng A, Hai Y, Zhuang J, Liu Y, Cheng M, Wei G. Fan R, et al. Among authors: lin r. Acta Pharm Sin B. 2024 Apr;14(4):1742-1758. doi: 10.1016/j.apsb.2023.11.032. Epub 2023 Dec 16. Acta Pharm Sin B. 2024. PMID: 38572099 Free PMC article.

5

A platinum(IV)-artesunate complex triggers ferroptosis by boosting cytoplasmic and mitochondrial lipid peroxidation to enhance tumor immunotherapy.

Fan R, Deng A, Lin R, Zhang S, Cheng C, Zhuang J, Hai Y, Zhao M, Yang L, Wei G. Fan R, et al. Among authors: lin r. MedComm (2020). 2024 May 20;5(6):e570. doi: 10.1002/mco2.570. eCollection 2024 Jun. MedComm (2020). 2024. PMID: 38774917 Free PMC article.

6

Massively parallel barcode sequencing revealed the interchangeability of capsule transporters in Streptococcus pneumoniae.

Chua WZ, Wong RLE, Chun YY, Shien NNC, Su T, Maiwald M, Chew KL, Lin RT, Hockenberry AM, Luo M, Sham LT. Chua WZ, et al. Among authors: lin rt. Sci Adv. 2025 Jan 24;11(4):eadr0162. doi: 10.1126/sciadv.adr0162. Epub 2025 Jan 24. Sci Adv. 2025. PMID: 39854462

7

Regulatory and retrograde signaling networks in the chlorophyll biosynthetic pathway.

Li Y, Cao T, Guo Y, Grimm B, Li X, Duanmu D, Lin R. Li Y, et al. Among authors: lin r. J Integr Plant Biol. 2025 Jan 24. doi: 10.1111/jipb.13837. Online ahead of print. J Integr Plant Biol. 2025. PMID: 39853950 Review.

8

Vegetation Fire Emissions Exacerbate Glacier Melting on the Third Pole.

You C, Wang J, Lin R, Xu C. You C, et al. Among authors: lin r. Environ Sci Technol. 2025 Jan 24. doi: 10.1021/acs.est.4c08090. Online ahead of print. Environ Sci Technol. 2025. PMID: 39853174

9

MiMeJF: Application of Coupled Matrix and Tensor Factorization (CMTF) for Enhanced Microbiome-Metabolome Multi-Omic Analysis.

Ou Z, Fu X, Norbäck D, Lin R, Wen J, Sun Y. Ou Z, et al. Among authors: lin r. Metabolites. 2025 Jan 14;15(1):51. doi: 10.3390/metabo15010051. Metabolites. 2025. PMID: 39852393

10

Deep learning-based drug screening for the discovery of potential therapeutic agents for Alzheimer's disease.

Wu T, Lin R, Cui P, Yong J, Yu H, Li Z. Wu T, et al. Among authors: lin r. J Pharm Anal. 2024 Oct;14(10):101022. doi: 10.1016/j.jpha.2024.101022. Epub 2024 Jun 13. J Pharm Anal. 2024. PMID: 39850238 Free PMC article.

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