Wei G - Search Results

1

Degradation of Hexokinase 2 Blocks Glycolysis and Induces GSDME-Dependent Pyroptosis to Amplify Immunogenic Cell Death for Breast Cancer Therapy.

Sang R, Fan R, Deng A, Gou J, Lin R, Zhao T, Hai Y, Song J, Liu Y, Qi B, Du G, Cheng M, Wei G. Sang R, et al. Among authors: wei g. J Med Chem. 2023 Jul 13;66(13):8464-8483. doi: 10.1021/acs.jmedchem.3c00118. Epub 2023 Jun 27. J Med Chem. 2023. PMID: 37376788

2

Au(I)-catalyzed triple bond alkoxylation/dienolether aromaticity-driven cascade cyclization to naphthalenes.

Liu Y, Guo J, Liu Y, Wang X, Wang Y, Jia X, Wei G, Chen L, Xiao J, Cheng M. Liu Y, et al. Among authors: wei g. Chem Commun (Camb). 2014 Jun 14;50(47):6243-5. doi: 10.1039/c4cc00464g. Epub 2014 May 1. Chem Commun (Camb). 2014. PMID: 24788234

3

Synthesis and evaluation of the anticancer activity of albiziabioside A and its analogues as apoptosis inducers against human melanoma cells.

Wei G, Wang S, Cui S, Guo J, Liu Y, Liu Y, Cheng M. Wei G, et al. Org Biomol Chem. 2014 Aug 21;12(31):5928-35. doi: 10.1039/c4ob00874j. Org Biomol Chem. 2014. PMID: 24985523

4

A library of 1,2,3-triazole-substituted oleanolic acid derivatives as anticancer agents: design, synthesis, and biological evaluation.

Wei G, Luan W, Wang S, Cui S, Li F, Liu Y, Liu Y, Cheng M. Wei G, et al. Org Biomol Chem. 2015 Feb 7;13(5):1507-14. doi: 10.1039/c4ob01605j. Org Biomol Chem. 2015. PMID: 25476168

5

Natural product-based design, synthesis and biological evaluation of Albiziabioside A derivatives that selectively induce HCT116 cell death.

Wei G, Cui S, Luan W, Wang S, Hou Z, Liu Y, Liu Y, Cheng M. Wei G, et al. Eur J Med Chem. 2016 May 4;113:92-101. doi: 10.1016/j.ejmech.2015.12.034. Epub 2015 Dec 21. Eur J Med Chem. 2016. PMID: 26922223

6

Dual-tail approach to discovery of novel carbonic anhydrase IX inhibitors by simultaneously matching the hydrophobic and hydrophilic halves of the active site.

Hou Z, Lin B, Bao Y, Yan HN, Zhang M, Chang XW, Zhang XX, Wang ZJ, Wei GF, Cheng MS, Liu Y, Guo C. Hou Z, et al. Eur J Med Chem. 2017 May 26;132:1-10. doi: 10.1016/j.ejmech.2017.03.023. Epub 2017 Mar 16. Eur J Med Chem. 2017. PMID: 28334643

7

Novel antitumor compound optimized from natural saponin Albiziabioside A induced caspase-dependent apoptosis and ferroptosis as a p53 activator through the mitochondrial pathway.

Wei G, Sun J, Hou Z, Luan W, Wang S, Cui S, Cheng M, Liu Y. Wei G, et al. Eur J Med Chem. 2018 Sep 5;157:759-772. doi: 10.1016/j.ejmech.2018.08.036. Epub 2018 Aug 14. Eur J Med Chem. 2018. PMID: 30142612

8

Natural Product Albiziabioside A Conjugated with Pyruvate Dehydrogenase Kinase Inhibitor Dichloroacetate To Induce Apoptosis-Ferroptosis-M2-TAMs Polarization for Combined Cancer Therapy.

Wei G, Sun J, Luan W, Hou Z, Wang S, Cui S, Cheng M, Liu Y. Wei G, et al. J Med Chem. 2019 Oct 10;62(19):8760-8772. doi: 10.1021/acs.jmedchem.9b00644. Epub 2019 Sep 27. J Med Chem. 2019. PMID: 31509699

9

CJ₂: A Novel Potent Platinum(IV) Prodrug Enhances Chemo-Immunotherapy by Facilitating PD-L1 Degradation in the Cytoplasm and Cytomembrane.

Fan R, Deng A, Qi B, Zhang S, Sang R, Luo L, Gou J, Liu Y, Lin R, Zhao M, Liu Y, Yang L, Cheng M, Wei G. Fan R, et al. Among authors: wei g. J Med Chem. 2023 Jan 12;66(1):875-889. doi: 10.1021/acs.jmedchem.2c01719. Epub 2023 Jan 3. J Med Chem. 2023. PMID: 36594812

10

A novel mitochondria-targeting DHODH inhibitor induces robust ferroptosis and alleviates immune suppression.

Hai Y, Fan R, Zhao T, Lin R, Zhuang J, Deng A, Meng S, Hou Z, Wei G. Hai Y, et al. Among authors: wei g. Pharmacol Res. 2024 Apr;202:107115. doi: 10.1016/j.phrs.2024.107115. Epub 2024 Feb 27. Pharmacol Res. 2024. PMID: 38423231 Free article.

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