Selection of functional variants of the NS3-NS4A protease of hepatitis C virus by using chimeric sindbis viruses.
Filocamo G, Pacini L, Nardi C, Bartholomew L, Scaturro M, Delmastro P, Tramontano A, De Francesco R, Migliaccio G.
Filocamo G, et al. Among authors: pacini l.
J Virol. 1999 Jan;73(1):561-75. doi: 10.1128/JVI.73.1.561-575.1999.
J Virol. 1999.
PMID: 9847361
Free PMC article.
NS3-NS4A gene sequences were fused to the gene coding for the Sindbis virus structural polyprotein in such a way that processing of the chimeric polyprotein, nucleocapsid assembly, and production of infectious viruses required NS3-NS4A-mediated proteolysis (G. Filocamo, L. …
NS3-NS4A gene sequences were fused to the gene coding for the Sindbis virus structural polyprotein in such a way that processing of the chim …