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Targeting Biomolecular Condensation and Protein Aggregation against Cancer.
Silva JL, Foguel D, Ferreira VF, Vieira TCRG, Marques MA, Ferretti GDS, Outeiro TF, Cordeiro Y, de Oliveira GAP. Silva JL, et al. Among authors: ferretti gds. Chem Rev. 2023 Jul 26;123(14):9094-9138. doi: 10.1021/acs.chemrev.3c00131. Epub 2023 Jun 28. Chem Rev. 2023. PMID: 37379327 Review.
Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands.
Petronilho EC, Pedrote MM, Marques MA, Passos YM, Mota MF, Jakobus B, de Sousa GDS, Pereira da Costa F, Felix AL, Ferretti GDS, Almeida FP, Cordeiro Y, Vieira TCRG, de Oliveira GAP, Silva JL. Petronilho EC, et al. Among authors: ferretti gds. Chem Sci. 2021 Apr 26;12(21):7334-7349. doi: 10.1039/d1sc01739j. Chem Sci. 2021. PMID: 34163823 Free PMC article.
Anticancer Therapeutic Strategies Targeting p53 Aggregation.
Ferretti GDS, Quarti J, Dos Santos G, Rangel LP, Silva JL. Ferretti GDS, et al. Int J Mol Sci. 2022 Sep 20;23(19):11023. doi: 10.3390/ijms231911023. Int J Mol Sci. 2022. PMID: 36232329 Free PMC article. Review.
Recent Synthetic Approaches towards Small Molecule Reactivators of p53.
Silva JL, Lima CGS, Rangel LP, Ferretti GDS, Pauli FP, Ribeiro RCB, da Silva TB, da Silva FC, Ferreira VF. Silva JL, et al. Among authors: ferretti gds. Biomolecules. 2020 Apr 20;10(4):635. doi: 10.3390/biom10040635. Biomolecules. 2020. PMID: 32326087 Free PMC article. Review.
11 results