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First-in-human study of a pharmacological duodenal exclusion therapy shows reduced postprandial glucose and insulin and increased bile acid and gut hormone concentrations.
Fineman MS, Bryant CLN, Colbert K, Jozefiak TH, Petersen JS, Horowitz M, Vora J, Rayner CK, Wabnitz P, Nimgaonkar A. Fineman MS, et al. Among authors: bryant cln. Diabetes Obes Metab. 2023 Sep;25(9):2447-2456. doi: 10.1111/dom.15066. Epub 2023 Jun 28. Diabetes Obes Metab. 2023. PMID: 37380614 Clinical Trial.
IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5.
Zhang J, Zhao R, Yu C, Bryant CLN, Wu K, Liu Z, Ding Y, Zhao Y, Xue B, Pan ZQ, Li C, Huang L, Fang L. Zhang J, et al. Among authors: bryant cln. J Proteome Res. 2020 Mar 6;19(3):1119-1130. doi: 10.1021/acs.jproteome.9b00626. Epub 2020 Feb 3. J Proteome Res. 2020. PMID: 31950832 Free PMC article.