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Page 1
Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
Chancellor A, Alan Simmons R, Khanolkar RC, Nosi V, Beshirova A, Berloffa G, Colombo R, Karuppiah V, Pentier JM, Tubb V, Ghadbane H, Suckling RJ, Page K, Crean RM, Vacchini A, De Gregorio C, Schaefer V, Constantin D, Gligoris T, Lloyd A, Hock M, Srikannathasan V, Robinson RA, Besra GS, van der Kamp MW, Mori L, Calogero R, Cole DK, De Libero G, Lepore M. Chancellor A, et al. Among authors: vacchini a. J Exp Med. 2023 Sep 4;220(9):e20221939. doi: 10.1084/jem.20221939. Epub 2023 Jun 29. J Exp Med. 2023. PMID: 37382893 Free PMC article.
MR1-Restricted T Cells Are Unprecedented Cancer Fighters.
Vacchini A, Chancellor A, Spagnuolo J, Mori L, De Libero G. Vacchini A, et al. Front Immunol. 2020 Apr 28;11:751. doi: 10.3389/fimmu.2020.00751. eCollection 2020. Front Immunol. 2020. PMID: 32411144 Free PMC article. Review.
MR1, an immunological periscope of cellular metabolism.
Chancellor A, Vacchini A, De Libero G. Chancellor A, et al. Among authors: vacchini a. Int Immunol. 2022 Feb 23;34(3):141-147. doi: 10.1093/intimm/dxab101. Int Immunol. 2022. PMID: 34718585 Free PMC article.
Surface protein and functional analyses identify CD4+CD39+ TCR αβ+ and activated TCR Vδ1+ cells with distinct pro-inflammatory functions in Crohn's disease lesions.
Devan J, Nosi V, Spagnuolo J, Chancellor A, Beshirova A, Loureiro JP, Vacchini A, Hendrik Niess J, Calogero R, Mori L, De Libero G, Hruz P. Devan J, et al. Among authors: vacchini a. Clin Exp Immunol. 2024 Jan 9;215(1):79-93. doi: 10.1093/cei/uxad098. Clin Exp Immunol. 2024. PMID: 37586415 Free PMC article.
Reduced G protein signaling despite impaired internalization and β-arrestin recruitment in patients carrying a CXCR4Leu317fsX3 mutation causing WHIM syndrome.
Kumar R, Milanesi S, Szpakowska M, Dotta L, Di Silvestre D, Trotta AM, Bello AM, Giacomelli M, Benedito M, Azevedo J, Pereira A, Cortesao E, Vacchini A, Castagna A, Pinelli M, Moratto D, Bonecchi R, Locati M, Scala S, Chevigné A, Borroni EM, Badolato R. Kumar R, et al. Among authors: vacchini a. JCI Insight. 2023 Mar 8;8(5):e145688. doi: 10.1172/jci.insight.145688. JCI Insight. 2023. PMID: 36883568 Free PMC article.
Phosphoproteomic mapping of CCR5 and ACKR2 signaling properties.
Vacchini A, Maffioli E, Di Silvestre D, Cancellieri C, Milanesi S, Nonnis S, Badanai S, Mauri P, Negri A, Locati M, Tedeschi G, Borroni EM. Vacchini A, et al. Front Mol Biosci. 2022 Nov 22;9:1060555. doi: 10.3389/fmolb.2022.1060555. eCollection 2022. Front Mol Biosci. 2022. PMID: 36483536 Free PMC article.
The carbonyl nucleobase adduct M3Ade is a potent antigen for adaptive polyclonal MR1-restricted T cells.
Chancellor A, Constantin D, Giuliano Berloffa, Yang Q, Nosi V, Loureiro JP, Colombo R, Jakob RP, Joss D, Pfeffer M, De Simone G, Morabito A, Schaefer V, Vacchini A, Brunelli L, Montagna D, Heim M, Zippelius A, Davoli E, Häussinger D, Maier T, Mori L, De Libero G. Chancellor A, et al. Among authors: vacchini a. Immunity. 2024 Dec 11:S1074-7613(24)00534-X. doi: 10.1016/j.immuni.2024.11.019. Online ahead of print. Immunity. 2024. PMID: 39701104 Free article.
20 results