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Comparison of colorimetric, fluorometric, and liquid chromatography-mass spectrometry assays for acetyl-coenzyme A.
Kantner DS, Megill E, Bostwick A, Yang V, Bekeova C, Van Scoyk A, Seifert E, Deininger MW, Snyder NW. Kantner DS, et al. Among authors: snyder nw. bioRxiv [Preprint]. 2023 Aug 15:2023.06.01.543311. doi: 10.1101/2023.06.01.543311. bioRxiv. 2023. Update in: Anal Biochem. 2024 Jan 15;685:115405. doi: 10.1016/j.ab.2023.115405 PMID: 37398224 Free PMC article. Updated. Preprint.
Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathy.
Flam E, Jang C, Murashige D, Yang Y, Morley MP, Jung S, Kantner DS, Pepper H, Bedi KC Jr, Brandimarto J, Prosser BL, Cappola T, Snyder NW, Rabinowitz JD, Margulies KB, Arany Z. Flam E, et al. Among authors: snyder nw. Nat Cardiovasc Res. 2022 Sep;1(9):817-829. doi: 10.1038/s44161-022-00117-6. Epub 2022 Aug 29. Nat Cardiovasc Res. 2022. PMID: 36776621 Free PMC article.
Acetate controls endothelial-to-mesenchymal transition.
Zhu X, Wang Y, Soaita I, Lee HW, Bae H, Boutagy N, Bostwick A, Zhang RM, Bowman C, Xu Y, Trefely S, Chen Y, Qin L, Sessa W, Tellides G, Jang C, Snyder NW, Yu L, Arany Z, Simons M. Zhu X, et al. Among authors: snyder nw. Cell Metab. 2023 Jul 11;35(7):1163-1178.e10. doi: 10.1016/j.cmet.2023.05.010. Epub 2023 Jun 15. Cell Metab. 2023. PMID: 37327791 Free PMC article.
De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression.
Tangudu NK, Buj R, Wang H, Wang J, Cole AR, Uboveja A, Fang R, Amalric A, Sajjakulnukit P, Lyons MA, Cooper K, Hempel N, Snyder NW, Lyssiotis CA, Chandran UR, Aird KM. Tangudu NK, et al. Among authors: snyder nw. bioRxiv [Preprint]. 2023 Sep 23:2023.07.15.549149. doi: 10.1101/2023.07.15.549149. bioRxiv. 2023. Update in: Cancer Res Commun. 2024 May 2;4(5):1174-1188. doi: 10.1158/2767-9764.CRC-23-0450 PMID: 37503050 Free PMC article. Updated. Preprint.
Lactoylglutathione promotes inflammatory signaling in macrophages through histone lactoylation.
Trujillo MN, Jennings EQ, Hoffman EA, Zhang H, Phoebe AM, Mastin GE, Kitamura N, Reisz JA, Megill E, Kantner D, Marcinkiewicz MM, Twardy SM, Lebario F, Chapman E, McCullough RL, D'Alessandro A, Snyder NW, Cusanovich DA, Galligan JJ. Trujillo MN, et al. Among authors: snyder nw. Mol Metab. 2024 Mar;81:101888. doi: 10.1016/j.molmet.2024.101888. Epub 2024 Feb 1. Mol Metab. 2024. PMID: 38307385 Free PMC article.
Acetate drives ovarian cancer quiescence via ACSS2-mediated acetyl-CoA production.
Sharrow AC, Megill E, Chen AJ, Farooqi A, Tangudu NK, Uboveja A, McGonigal S, Hempel N, Snyder NW, Buckanovich RJ, Aird KM. Sharrow AC, et al. Among authors: snyder nw. Mol Metab. 2024 Nov;89:102031. doi: 10.1016/j.molmet.2024.102031. Epub 2024 Sep 19. Mol Metab. 2024. PMID: 39304063 Free PMC article.
Bempedoic acid suppresses diet-induced hepatic steatosis independently of ATP-citrate lyase.
Liu JY, Kuna RS, Pinheiro LV, Nguyen PTT, Welles JE, Drummond JM, Murali N, Sharma PV, Supplee JG, Shiue M, Zhao S, Farria AT, Kumar A, Ruchhoeft ML, Demetriadou C, Kantner DS, Chatoff A, Megill E, Titchenell PM, Snyder NW, Metallo CM, Wellen KE. Liu JY, et al. Among authors: snyder nw. Cell Metab. 2025 Jan 7;37(1):239-254.e7. doi: 10.1016/j.cmet.2024.10.014. Epub 2024 Oct 28. Cell Metab. 2025. PMID: 39471816
142 results