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Page 1
Spatial mapping of cellular senescence: emerging challenges and opportunities.
Gurkar AU, Gerencser AA, Mora AL, Nelson AC, Zhang AR, Lagnado AB, Enninful A, Benz C, Furman D, Beaulieu D, Jurk D, Thompson EL, Wu F, Rodriguez F, Barthel G, Chen H, Phatnani H, Heckenbach I, Chuang JH, Horrell J, Petrescu J, Alder JK, Lee JH, Niedernhofer LJ, Kumar M, Königshoff M, Bueno M, Sokka M, Scheibye-Knudsen M, Neretti N, Eickelberg O, Adams PD, Hu Q, Zhu Q, Porritt RA, Dong R, Peters S, Victorelli S, Pengo T, Khaliullin T, Suryadevara V, Fu X, Bar-Joseph Z, Ji Z, Passos JF. Gurkar AU, et al. Among authors: eickelberg o. Nat Aging. 2023 Jul;3(7):776-790. doi: 10.1038/s43587-023-00446-6. Epub 2023 Jul 3. Nat Aging. 2023. PMID: 37400722 Free PMC article. Review.
An integrated cell atlas of the lung in health and disease.
Sikkema L, Ramírez-Suástegui C, Strobl DC, Gillett TE, Zappia L, Madissoon E, Markov NS, Zaragosi LE, Ji Y, Ansari M, Arguel MJ, Apperloo L, Banchero M, Bécavin C, Berg M, Chichelnitskiy E, Chung MI, Collin A, Gay ACA, Gote-Schniering J, Hooshiar Kashani B, Inecik K, Jain M, Kapellos TS, Kole TM, Leroy S, Mayr CH, Oliver AJ, von Papen M, Peter L, Taylor CJ, Walzthoeni T, Xu C, Bui LT, De Donno C, Dony L, Faiz A, Guo M, Gutierrez AJ, Heumos L, Huang N, Ibarra IL, Jackson ND, Kadur Lakshminarasimha Murthy P, Lotfollahi M, Tabib T, Talavera-López C, Travaglini KJ, Wilbrey-Clark A, Worlock KB, Yoshida M; Lung Biological Network Consortium; van den Berge M, Bossé Y, Desai TJ, Eickelberg O, Kaminski N, Krasnow MA, Lafyatis R, Nikolic MZ, Powell JE, Rajagopal J, Rojas M, Rozenblatt-Rosen O, Seibold MA, Sheppard D, Shepherd DP, Sin DD, Timens W, Tsankov AM, Whitsett J, Xu Y, Banovich NE, Barbry P, Duong TE, Falk CS, Meyer KB, Kropski JA, Pe'er D, Schiller HB, Tata PR, Schultze JL, Teichmann SA, Misharin AV, Nawijn MC, Luecken MD, Theis FJ. Sikkema L, et al. Among authors: eickelberg o. Nat Med. 2023 Jun;29(6):1563-1577. doi: 10.1038/s41591-023-02327-2. Epub 2023 Jun 8. Nat Med. 2023. PMID: 37291214 Free PMC article.
Fibroblast-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis.
Burgy O, Mayr CH, Schenesse D, Fousekis Papakonstantinou E, Ballester B, Sengupta A, She Y, Hu Q, Melo-Narvaéz MC, Jain E, Pestoni JC, Mozurak M, Estrada-Bernal A, Onwuka U, Coughlan C, Parimon T, Chen P, Heimerl T, Bange G, Schmeck BT, Lindner M, Hilgendorff A, Ruppert C, Güenther A, Mann M, Yildirim AÖ, Eickelberg O, Jung AL, Schiller HB, Lehmann M, Burgstaller G, Königshoff M. Burgy O, et al. Among authors: eickelberg o. JCI Insight. 2024 Aug 15;9(18):e168889. doi: 10.1172/jci.insight.168889. JCI Insight. 2024. PMID: 39315549 Free PMC article.
scDOT: optimal transport for mapping senescent cells in spatial transcriptomics.
Nguyen ND, Rosas L, Khaliullin T, Jiang P, Hasanaj E, Ovando-Ricardez JA, Bueno M, Rahman I, Pryhuber GS, Li D, Ma Q, Finkel T, Königshoff M, Eickelberg O, Rojas M, Mora AL, Lugo-Martinez J, Bar-Joseph Z. Nguyen ND, et al. Among authors: eickelberg o. Genome Biol. 2024 Nov 8;25(1):288. doi: 10.1186/s13059-024-03426-0. Genome Biol. 2024. PMID: 39516853 Free PMC article.
Lung Epithelium Releases Growth Differentiation Factor 15 in Response to Pathogen-mediated Injury.
Shah FA, Bahudhanapati H, Jiang M, Tabary M, van der Geest R, Tolman NJ, Kochin M, Xiong Z, Al-Yousif N, Sayed K, Benos PV, Raffensperger K, Evankovich J, Neal MD, Snyder ME, Eickelberg O, Ray P, Dela Cruz C, Bon J, McVerry BJ, Straub AC, Jurczak MJ, Suber TL, Zhang Y, Chen K, Kitsios GD, Lee JS, Alder JK, Bain WG. Shah FA, et al. Among authors: eickelberg o. Am J Respir Cell Mol Biol. 2024 May;70(5):379-391. doi: 10.1165/rcmb.2023-0429OC. Am J Respir Cell Mol Biol. 2024. PMID: 38301257 Free PMC article.
COPD basal cells are primed towards secretory to multiciliated cell imbalance driving increased resilience to environmental stressors.
Stoleriu MG, Ansari M, Strunz M, Schamberger A, Heydarian M, Ding Y, Voss C, Schneider JJ, Gerckens M, Burgstaller G, Castelblanco A, Kauke T, Fertmann J, Schneider C, Behr J, Lindner M, Stacher-Priehse E, Irmler M, Beckers J, Eickelberg O, Schubert B, Hauck SM, Schmid O, Hatz RA, Stoeger T, Schiller HB, Hilgendorff A. Stoleriu MG, et al. Among authors: eickelberg o. Thorax. 2024 May 20;79(6):524-537. doi: 10.1136/thorax-2022-219958. Thorax. 2024. PMID: 38286613 Free PMC article.
304 results