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The state-of-the-art of N-of-1 therapies and the IRDiRC N-of-1 development roadmap.
Jonker AH, Tataru EA, Graessner H, Dimmock D, Jaffe A, Baynam G, Davies J, Mitkus S, Iliach O, Horgan R, Augustine EF, Bateman-House A, Pasmooij AMG, Yu T, Synofzik M, Douville J, Lapteva L, Brooks PJ, O'Connor D, Aartsma-Rus A; N-of-1 Task Force of the International Rare Diseases Research Consortium (IRDiRC). Jonker AH, et al. Among authors: brooks pj. Nat Rev Drug Discov. 2024 Nov 4. doi: 10.1038/s41573-024-01059-3. Online ahead of print. Nat Rev Drug Discov. 2024. PMID: 39496921 Review.
Whole-brain annotation and multi-connectome cell typing of Drosophila.
Schlegel P, Yin Y, Bates AS, Dorkenwald S, Eichler K, Brooks P, Han DS, Gkantia M, Dos Santos M, Munnelly EJ, Badalamente G, Serratosa Capdevila L, Sane VA, Fragniere AMC, Kiassat L, Pleijzier MW, Stürner T, Tamimi IFM, Dunne CR, Salgarella I, Javier A, Fang S, Perlman E, Kazimiers T, Jagannathan SR, Matsliah A, Sterling AR, Yu SC, McKellar CE; FlyWire Consortium; Costa M, Seung HS, Murthy M, Hartenstein V, Bock DD, Jefferis GSXE. Schlegel P, et al. Among authors: brooks p. Nature. 2024 Oct;634(8032):139-152. doi: 10.1038/s41586-024-07686-5. Epub 2024 Oct 2. Nature. 2024. PMID: 39358521 Free PMC article.
Neuronal wiring diagram of an adult brain.
Dorkenwald S, Matsliah A, Sterling AR, Schlegel P, Yu SC, McKellar CE, Lin A, Costa M, Eichler K, Yin Y, Silversmith W, Schneider-Mizell C, Jordan CS, Brittain D, Halageri A, Kuehner K, Ogedengbe O, Morey R, Gager J, Kruk K, Perlman E, Yang R, Deutsch D, Bland D, Sorek M, Lu R, Macrina T, Lee K, Bae JA, Mu S, Nehoran B, Mitchell E, Popovych S, Wu J, Jia Z, Castro MA, Kemnitz N, Ih D, Bates AS, Eckstein N, Funke J, Collman F, Bock DD, Jefferis GSXE, Seung HS, Murthy M; FlyWire Consortium. Dorkenwald S, et al. Nature. 2024 Oct;634(8032):124-138. doi: 10.1038/s41586-024-07558-y. Epub 2024 Oct 2. Nature. 2024. PMID: 39358518 Free PMC article.
Deep immune cell phenotyping and induced immune cell responses at admission stratified by BMI in patients hospitalized with COVID-19: An observational multicenter cohort pilot study.
Sejdic A, Hartling HJ, Gitz Holler J, Klingen Gjærde L, Matovu Dungu A, Engel Møller ME, Svanberg Teglgaard R, Utoft Niemann CU, Brooks PT, Mogensen TH, Weis N, Podlekareva D, Baum Jørgensen ML, Ortved Gang A, Stampe Hersby D, Hald A, Dam Nielsen S, Lebech AM, Helleberg M, Lundgren J, Træholt Franck K, Fischer TK, Barrella Harboe Z, Marquart HV, Rye Ostrowski S, Lindegaard B. Sejdic A, et al. Among authors: brooks pt. Clin Immunol. 2024 Oct;267:110336. doi: 10.1016/j.clim.2024.110336. Epub 2024 Aug 6. Clin Immunol. 2024. PMID: 39117044 Free article.
1,286 results