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Page 1
Early detection of ovarian cancer using cell-free DNA fragmentomes and protein biomarkers.
Medina JE, Annapragada AV, Lof P, Short S, Bartolomucci AL, Mathios D, Koul S, Niknafs N, Noe M, Foda ZH, Bruhm DC, Hruban C, Vulpescu NA, Jung E, Dua R, Canzoniero JV, Cristiano S, Adleff V, Symecko H, van den Broek D, Sokoll LJ, Baylin SB, Press MF, Slamon DJ, Konecny GE, Therkildsen C, Carvalho B, Meijer GA, Andersen CL, Domchek SM, Drapkin R, Scharpf RB, Phallen J, Lok CAR, Velculescu VE. Medina JE, et al. Among authors: phallen j. Cancer Discov. 2024 Sep 30. doi: 10.1158/2159-8290.CD-24-0393. Online ahead of print. Cancer Discov. 2024. PMID: 39345137
Early evaluation of the effectiveness and cost-effectiveness of ctDNA-guided selection for adjuvant chemotherapy in stage II colon cancer.
Kramer A, Greuter MJE, Schraa SJ, Vink GR, Phallen J, Velculescu VE, Meijer GA, van den Broek D, Koopman M, Roodhart JML, Fijneman RJA, Retèl VP, Coupé VMH. Kramer A, et al. Among authors: phallen j. Ther Adv Med Oncol. 2024 Aug 21;16:17588359241266164. doi: 10.1177/17588359241266164. eCollection 2024. Ther Adv Med Oncol. 2024. PMID: 39175989 Free PMC article.
DNA methylation and gene expression as determinants of genome-wide cell-free DNA fragmentation.
Noë M, Mathios D, Annapragada AV, Koul S, Foda ZH, Medina JE, Cristiano S, Cherry C, Bruhm DC, Niknafs N, Adleff V, Ferreira L, Easwaran H, Baylin S, Phallen J, Scharpf RB, Velculescu VE. Noë M, et al. Among authors: phallen j. Nat Commun. 2024 Aug 6;15(1):6690. doi: 10.1038/s41467-024-50850-8. Nat Commun. 2024. PMID: 39107309 Free PMC article.
Genome-wide repeat landscapes in cancer and cell-free DNA.
Annapragada AV, Niknafs N, White JR, Bruhm DC, Cherry C, Medina JE, Adleff V, Hruban C, Mathios D, Foda ZH, Phallen J, Scharpf RB, Velculescu VE. Annapragada AV, et al. Among authors: phallen j. Sci Transl Med. 2024 Mar 13;16(738):eadj9283. doi: 10.1126/scitranslmed.adj9283. Epub 2024 Mar 13. Sci Transl Med. 2024. PMID: 38478628 Free PMC article.
Elucidating the Heterogeneity of Immunotherapy Response and Immune-Related Toxicities by Longitudinal ctDNA and Immune Cell Compartment Tracking in Lung Cancer.
Murray JC, Sivapalan L, Hummelink K, Balan A, White JR, Niknafs N, Rhymee L, Pereira G, Rao N, Weksler B, Bahary N, Phallen J, Leal A, Bartlett DL, Marrone KA, Naidoo J, Goel A, Levy B, Rosner S, Hann CL, Scott SC, Feliciano J, Lam VK, Ettinger DS, Li QK, Illei PB, Monkhorst K, Scharpf RB, Brahmer JR, Velculescu VE, Zaidi AH, Forde PM, Anagnostou V. Murray JC, et al. Among authors: phallen j. Clin Cancer Res. 2024 Jan 17;30(2):389-403. doi: 10.1158/1078-0432.CCR-23-1469. Clin Cancer Res. 2024. PMID: 37939140 Free PMC article.
Single-molecule genome-wide mutation profiles of cell-free DNA for non-invasive detection of cancer.
Bruhm DC, Mathios D, Foda ZH, Annapragada AV, Medina JE, Adleff V, Chiao EJ, Ferreira L, Cristiano S, White JR, Mazzilli SA, Billatos E, Spira A, Zaidi AH, Mueller J, Kim AK, Anagnostou V, Phallen J, Scharpf RB, Velculescu VE. Bruhm DC, et al. Among authors: phallen j. Nat Genet. 2023 Aug;55(8):1301-1310. doi: 10.1038/s41588-023-01446-3. Epub 2023 Jul 27. Nat Genet. 2023. PMID: 37500728 Free PMC article.
Elucidating the heterogeneity of immunotherapy response and immune-related toxicities by longitudinal ctDNA and immune cell compartment tracking in lung cancer.
Murray JC, Sivapalan L, Hummelink K, Balan A, White JR, Niknafs N, Rhymee L, Pereira G, Rao N, Phallen J, Leal A, Bartlett DL, Marrone KA, Naidoo J, Levy B, Rosner S, Hann CL, Scott SC, Feliciano J, Lam VK, Ettinger DS, Li QK, Illei PB, Monkhorst K, Zaidi AH, Scharpf RB, Brahmer JR, Velculescu VE, Forde PM, Anagnostou V. Murray JC, et al. Among authors: phallen j. bioRxiv [Preprint]. 2023 Jun 26:2023.06.23.546338. doi: 10.1101/2023.06.23.546338. bioRxiv. 2023. Update in: Clin Cancer Res. 2024 Jan 17;30(2):389-403. doi: 10.1158/1078-0432.CCR-23-1469 PMID: 37425893 Free PMC article. Updated. Preprint.
Cell-Free DNA Fragmentomes in the Diagnostic Evaluation of Patients With Symptoms Suggestive of Lung Cancer.
Leal AIC, Mathios D, Jakubowski D, Johansen JS, Lau A, Wu T, Cristiano S, Medina JE, Phallen J, Bruhm DC, Carey J, Dracopoli NC, Bojesen SE, Scharpf RB, Velculescu VE, Vachani A, Bach PB. Leal AIC, et al. Among authors: phallen j. Chest. 2023 Oct;164(4):1019-1027. doi: 10.1016/j.chest.2023.04.033. Epub 2023 Apr 26. Chest. 2023. PMID: 37116747 Free article.
Metastatic Colorectal Cancer Treatment Response Evaluation by Ultra-Deep Sequencing of Cell-Free DNA and Matched White Blood Cells.
van 't Erve I, Medina JE, Leal A, Papp E, Phallen J, Adleff V, Chiao EJ, Arun AS, Bolhuis K, Simmons JK, Karandikar A, Valkenburg KC, Sausen M, Angiuoli SV, Scharpf RB, Punt CJA, Meijer GA, Velculescu VE, Fijneman RJA. van 't Erve I, et al. Among authors: phallen j. Clin Cancer Res. 2023 Mar 1;29(5):899-909. doi: 10.1158/1078-0432.CCR-22-2538. Clin Cancer Res. 2023. PMID: 36534496 Free PMC article. Clinical Trial.
Detecting Liver Cancer Using Cell-Free DNA Fragmentomes.
Foda ZH, Annapragada AV, Boyapati K, Bruhm DC, Vulpescu NA, Medina JE, Mathios D, Cristiano S, Niknafs N, Luu HT, Goggins MG, Anders RA, Sun J, Meta SH, Thomas DL, Kirk GD, Adleff V, Phallen J, Scharpf RB, Kim AK, Velculescu VE. Foda ZH, et al. Among authors: phallen j. Cancer Discov. 2023 Mar 1;13(3):616-631. doi: 10.1158/2159-8290.CD-22-0659. Cancer Discov. 2023. PMID: 36399356 Free PMC article.
38 results