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Soluble amyloid beta-containing aggregates are present throughout the brain at early stages of Alzheimer's disease.
Sideris DI, Danial JSH, Emin D, Ruggeri FS, Xia Z, Zhang YP, Lobanova E, Dakin H, De S, Miller A, Sang JC, Knowles TPJ, Vendruscolo M, Fraser G, Crowther D, Klenerman D. Sideris DI, et al. Among authors: xia z. Brain Commun. 2021 Jul 2;3(3):fcab147. doi: 10.1093/braincomms/fcab147. eCollection 2021. Brain Commun. 2021. PMID: 34396107 Free PMC article.
Small soluble α-synuclein aggregates are the toxic species in Parkinson's disease.
Emin D, Zhang YP, Lobanova E, Miller A, Li X, Xia Z, Dakin H, Sideris DI, Lam JYL, Ranasinghe RT, Kouli A, Zhao Y, De S, Knowles TPJ, Vendruscolo M, Ruggeri FS, Aigbirhio FI, Williams-Gray CH, Klenerman D. Emin D, et al. Among authors: xia z. Nat Commun. 2022 Sep 20;13(1):5512. doi: 10.1038/s41467-022-33252-6. Nat Commun. 2022. PMID: 36127374 Free PMC article.
Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer's disease.
Xia Z, Prescott EE, Urbanek A, Wareing HE, King MC, Olerinyova A, Dakin H, Leah T, Barnes KA, Matuszyk MM, Dimou E, Hidari E, Zhang YP, Lam JYL, Danial JSH, Strickland MR, Jiang H, Thornton P, Crowther DC, Ohtonen S, Gómez-Budia M, Bell SM, Ferraiuolo L, Mortiboys H, Higginbottom A, Wharton SB, Holtzman DM, Malm T, Ranasinghe RT, Klenerman D, De S. Xia Z, et al. Nat Commun. 2024 Jun 1;15(1):4695. doi: 10.1038/s41467-024-49028-z. Nat Commun. 2024. PMID: 38824138 Free PMC article.
6,340 results