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Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes.
Errico S, Lucchesi G, Odino D, Osman EY, Cascella R, Neri L, Capitini C, Calamai M, Bemporad F, Cecchi C, Kinney WA, Barbut D, Relini A, Canale C, Caminati G, Limbocker R, Vendruscolo M, Zasloff M, Chiti F. Errico S, et al. Among authors: vendruscolo m. J Med Chem. 2023 Jul 27;66(14):9519-9536. doi: 10.1021/acs.jmedchem.3c00182. Epub 2023 Jul 11. J Med Chem. 2023. PMID: 37433124 Free PMC article.
Biological function in a non-native partially folded state of a protein.
Bemporad F, Gsponer J, Hopearuoho HI, Plakoutsi G, Stati G, Stefani M, Taddei N, Vendruscolo M, Chiti F. Bemporad F, et al. Among authors: vendruscolo m. EMBO J. 2008 May 21;27(10):1525-35. doi: 10.1038/emboj.2008.82. Epub 2008 May 1. EMBO J. 2008. PMID: 18451804 Free PMC article.
Prediction of aggregation-prone regions in structured proteins.
Tartaglia GG, Pawar AP, Campioni S, Dobson CM, Chiti F, Vendruscolo M. Tartaglia GG, et al. Among authors: vendruscolo m. J Mol Biol. 2008 Jul 4;380(2):425-36. doi: 10.1016/j.jmb.2008.05.013. Epub 2008 May 13. J Mol Biol. 2008. PMID: 18514226
Intrinsic determinants of neurotoxic aggregate formation by the amyloid beta peptide.
Brorsson AC, Bolognesi B, Tartaglia GG, Shammas SL, Favrin G, Watson I, Lomas DA, Chiti F, Vendruscolo M, Dobson CM, Crowther DC, Luheshi LM. Brorsson AC, et al. Among authors: vendruscolo m. Biophys J. 2010 Apr 21;98(8):1677-84. doi: 10.1016/j.bpj.2009.12.4320. Biophys J. 2010. PMID: 20409489 Free PMC article.
536 results