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Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5.
Brusa I, Sondo E, Pesce E, Tomati V, Gioia D, Falchi F, Balboni B, Ortega Martínez JA, Veronesi M, Romeo E, Margaroli N, Recanatini M, Girotto S, Pedemonte N, Roberti M, Cavalli A. Brusa I, et al. Among authors: pedemonte n. J Med Chem. 2023 Jul 27;66(14):9797-9822. doi: 10.1021/acs.jmedchem.3c00608. Epub 2023 Jul 13. J Med Chem. 2023. PMID: 37440686 Free PMC article.
Gelsolin secretion in interleukin-4-treated bronchial epithelia and in asthmatic airways.
Candiano G, Bruschi M, Pedemonte N, Caci E, Liberatori S, Bini L, Pellegrini C, Viganò M, O'Connor BJ, Lee TH, Galietta LJ, Zegarra-Moran O. Candiano G, et al. Among authors: pedemonte n. Am J Respir Crit Care Med. 2005 Nov 1;172(9):1090-6. doi: 10.1164/rccm.200409-1185OC. Epub 2005 Aug 11. Am J Respir Crit Care Med. 2005. PMID: 16100010
Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening.
Kalid O, Mense M, Fischman S, Shitrit A, Bihler H, Ben-Zeev E, Schutz N, Pedemonte N, Thomas PJ, Bridges RJ, Wetmore DR, Marantz Y, Senderowitz H. Kalid O, et al. Among authors: pedemonte n. J Comput Aided Mol Des. 2010 Dec;24(12):971-91. doi: 10.1007/s10822-010-9390-0. Epub 2010 Oct 26. J Comput Aided Mol Des. 2010. PMID: 20976528 Free PMC article.
112 results