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Page 1
Axitinib: A Photoswitchable Approved Tyrosine Kinase Inhibitor.
Schmidt D, Rodat T, Heintze L, Weber J, Horbert R, Girreser U, Raeker T, Bußmann L, Kriegs M, Hartke B, Peifer C. Schmidt D, et al. Among authors: kriegs m. ChemMedChem. 2018 Nov 20;13(22):2415-2426. doi: 10.1002/cmdc.201800531. Epub 2018 Nov 5. ChemMedChem. 2018. PMID: 30199151
Analyzing expression and phosphorylation of the EGF receptor in HNSCC.
Kriegs M, Clauditz TS, Hoffer K, Bartels J, Buhs S, Gerull H, Zech HB, Bußmann L, Struve N, Rieckmann T, Petersen C, Betz CS, Rothkamm K, Nollau P, Münscher A. Kriegs M, et al. Sci Rep. 2019 Sep 19;9(1):13564. doi: 10.1038/s41598-019-49885-5. Sci Rep. 2019. PMID: 31537844 Free PMC article.
EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma.
Struve N, Binder ZA, Stead LF, Brend T, Bagley SJ, Faulkner C, Ott L, Müller-Goebel J, Weik AS, Hoffer K, Krug L, Rieckmann T, Bußmann L, Henze M, Morrissette JJD, Kurian KM, Schüller U, Petersen C, Rothkamm K, O Rourke DM, Short SC, Kriegs M. Struve N, et al. Among authors: kriegs m. Oncogene. 2020 Apr;39(15):3041-3055. doi: 10.1038/s41388-020-1208-5. Epub 2020 Feb 17. Oncogene. 2020. PMID: 32066879 Free PMC article.
Analyzing tyrosine kinase activity in head and neck cancer by functional kinomics: Identification of hyperactivated Src family kinases as prognostic markers and potential targets.
Bußmann L, Hoffer K, von Bargen CM, Droste C, Lange T, Kemmling J, Schröder-Schwarz J, Vu AT, Akingunsade L, Nollau P, Rangarajan S, de Wijn R, Oetting A, Müller C, Böckelmann LC, Zech HB, Berger JC, Möckelmann N, Busch CJ, Böttcher A, Gatzemeier F, Klinghammer K, Simnica D, Binder M, Struve N, Rieckmann T, Schumacher U, Clauditz TS, Betz CS, Petersen C, Rothkamm K, Münscher A, Kriegs M. Bußmann L, et al. Among authors: kriegs m. Int J Cancer. 2021 Sep 1;149(5):1166-1180. doi: 10.1002/ijc.33606. Epub 2021 May 7. Int J Cancer. 2021. PMID: 33890294
Kinomic comparison of snap frozen and ex vivo-cultured head and neck tumors.
Berger J, Zech HB, Hoffer K, von Bargen CM, Nordquist L, Bussmann L, Gatzemeier F, Busch CJ, Möckelmann N, Münscher A, Betz CS, Petersen C, Rothkamm K, Rieckmann T, Köcher S, Kriegs M. Berger J, et al. Among authors: kriegs m. Oral Oncol. 2021 Dec;123:105603. doi: 10.1016/j.oraloncology.2021.105603. Epub 2021 Nov 16. Oral Oncol. 2021. PMID: 34798574 Free article.
Patient derived ex vivo tissue slice cultures demonstrate a profound DNA double-strand break repair defect in HPV-positive oropharyngeal head and neck cancer.
Zech HB, Berger J, Mansour WY, Nordquist L, von Bargen CM, Bußmann L, Oetting A, Christiansen S, Möckelmann N, Böttcher A, Busch CJ, Petersen C, Betz C, Rothkamm K, Kriegs M, Köcher S, Rieckmann T. Zech HB, et al. Among authors: kriegs m. Radiother Oncol. 2022 Mar;168:138-146. doi: 10.1016/j.radonc.2022.01.017. Epub 2022 Jan 29. Radiother Oncol. 2022. PMID: 35093407
Increased replication stress and R-loop accumulation in EGFRvIII-expressing glioblastoma present new therapeutic opportunities.
Struve N, Hoffer K, Weik AS, Riepen B, Krug L, Cetin MH, Burmester J, Ott L, Liebing J, Gatzemeier F, Müller-Goebel J, Gerbach M, Bußmann L, Parplys AC, Unger K, Mansour WY, Schüller U, Rieckmann T, Petersen C, Rothkamm K, Short SC, Kriegs M. Struve N, et al. Among authors: kriegs m. Neurooncol Adv. 2021 Dec 4;4(1):vdab180. doi: 10.1093/noajnl/vdab180. eCollection 2022 Jan-Dec. Neurooncol Adv. 2021. PMID: 35274102 Free PMC article.
68 results