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Page 1
Mitochondria Transplantation Mitigates Damage in an In Vitro Model of Renal Tubular Injury and in an Ex Vivo Model of DCD Renal Transplantation.
Rossi A, Asthana A, Riganti C, Sedrakyan S, Byers LN, Robertson J, Senger RS, Montali F, Grange C, Dalmasso A, Porporato PE, Palles C, Thornton ME, Da Sacco S, Perin L, Ahn B, McCully J, Orlando G, Bussolati B. Rossi A, et al. Among authors: porporato pe. Ann Surg. 2023 Dec 1;278(6):e1313-e1326. doi: 10.1097/SLA.0000000000006005. Epub 2023 Jul 14. Ann Surg. 2023. PMID: 37450698 Free PMC article.
RICTOR/mTORC2 downregulation in BRAFV600E melanoma cells promotes resistance to BRAF/MEK inhibition.
Ponzone L, Audrito V, Landi C, Moiso E, Levra Levron C, Ferrua S, Savino A, Vitale N, Gasparrini M, Avalle L, Vantaggiato L, Shaba E, Tassone B, Saoncella S, Orso F, Viavattene D, Marina E, Fiorilla I, Burrone G, Abili Y, Altruda F, Bini L, Deaglio S, Defilippi P, Menga A, Poli V, Porporato PE, Provero P, Raffaelli N, Riganti C, Taverna D, Cavallo F, Calautti E. Ponzone L, et al. Among authors: porporato pe. Mol Cancer. 2024 May 16;23(1):105. doi: 10.1186/s12943-024-02010-1. Mol Cancer. 2024. PMID: 38755661 Free PMC article.
Flvcr1a deficiency promotes heme-based energy metabolism dysfunction in skeletal muscle.
Mistretta M, Fiorito V, Allocco AL, Ammirata G, Hsu MY, Digiovanni S, Belicchi M, Napoli L, Ripolone M, Trombetta E, Mauri P, Farini A, Meregalli M, Villa C, Porporato PE, Miniscalco B, Crich SG, Riganti C, Torrente Y, Tolosano E. Mistretta M, et al. Among authors: porporato pe. Cell Rep. 2024 Mar 26;43(3):113854. doi: 10.1016/j.celrep.2024.113854. Epub 2024 Feb 26. Cell Rep. 2024. PMID: 38412099 Free article.
Systemic metabolic crosstalk as driver of cancer cachexia.
Wyart E, Carrà G, Angelino E, Penna F, Porporato PE. Wyart E, et al. Among authors: porporato pe. Trends Endocrinol Metab. 2025 Jan 4:S1043-2760(24)00327-8. doi: 10.1016/j.tem.2024.12.005. Online ahead of print. Trends Endocrinol Metab. 2025. PMID: 39757061 Review.
Metabolic plasticity in pancreatic cancer: The mitochondrial connection.
Ghiglione N, Abbo D, Bushunova A, Costamagna A, Porporato PE, Martini M. Ghiglione N, et al. Among authors: porporato pe. Mol Metab. 2024 Dec 28;92:102089. doi: 10.1016/j.molmet.2024.102089. Online ahead of print. Mol Metab. 2024. PMID: 39736443 Free article. Review.
FK506 bypasses the effect of erythroferrone in cancer cachexia skeletal muscle atrophy.
Mina E, Wyart E, Sartori R, Angelino E, Zaggia I, Rausch V, Maldotti M, Pagani A, Hsu MY, Friziero A, Sperti C, Menga A, Graziani A, Hirsch E, Oliviero S, Sandri M, Conti L, Kautz L, Silvestri L, Porporato PE. Mina E, et al. Among authors: porporato pe. Cell Rep Med. 2023 Dec 19;4(12):101306. doi: 10.1016/j.xcrm.2023.101306. Epub 2023 Dec 4. Cell Rep Med. 2023. PMID: 38052214 Free PMC article.
NAD+ repletion with niacin counteracts cancer cachexia.
Beltrà M, Pöllänen N, Fornelli C, Tonttila K, Hsu MY, Zampieri S, Moletta L, Corrà S, Porporato PE, Kivelä R, Viscomi C, Sandri M, Hulmi JJ, Sartori R, Pirinen E, Penna F. Beltrà M, et al. Among authors: porporato pe. Nat Commun. 2023 Apr 3;14(1):1849. doi: 10.1038/s41467-023-37595-6. Nat Commun. 2023. PMID: 37012289 Free PMC article.
Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer.
De Santis MC, Gozzelino L, Margaria JP, Costamagna A, Ratto E, Gulluni F, Di Gregorio E, Mina E, Lorito N, Bacci M, Lattanzio R, Sala G, Cappello P, Novelli F, Giovannetti E, Vicentini C, Andreani S, Delfino P, Corbo V, Scarpa A, Porporato PE, Morandi A, Hirsch E, Martini M. De Santis MC, et al. Among authors: porporato pe. Gut. 2023 Feb;72(2):360-371. doi: 10.1136/gutjnl-2021-325117. Epub 2022 May 27. Gut. 2023. PMID: 35623884 Free PMC article.
IFI16 Impacts Metabolic Reprogramming during Human Cytomegalovirus Infection.
Griffante G, Hewelt-Belka W, Albano C, Gugliesi F, Pasquero S, Castillo Pacheco SF, Bajetto G, Porporato PE, Mina E, Vallino M, Krapp C, Jakobsen MR, Purdy J, von Einem J, Landolfo S, Dell'Oste V, Biolatti M. Griffante G, et al. Among authors: porporato pe. mBio. 2022 Jun 28;13(3):e0043522. doi: 10.1128/mbio.00435-22. Epub 2022 Apr 14. mBio. 2022. PMID: 35420480 Free PMC article.
77 results