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Protection of pancreatic islets from oxidative cell death by a peripherally-active morphinan with increased drug safety.
Scholz O, Huß E, Otter S, Herebian D, Hamacher A, Levy LM, Hristeva S, Sanz M, Ajani H, Puentes AR, Hoffmann T, Hogeback J, Unger A, Terheyden S, Reina do Fundo M, Dewidar B, Roden M, Lammert E. Scholz O, et al. Among authors: hamacher a. Mol Metab. 2023 Sep;75:101775. doi: 10.1016/j.molmet.2023.101775. Epub 2023 Jul 12. Mol Metab. 2023. PMID: 37451343 Free PMC article.
Peripherally active dextromethorphan derivatives lower blood glucose levels by targeting pancreatic islets.
Scholz O, Otter S, Welters A, Wörmeyer L, Dolenšek J, Klemen MS, Pohorec V, Eberhard D, Mrugala J, Hamacher A, Koch A, Sanz M, Hoffmann T, Hogeback J, Herebian D, Klöcker N, Piechot A, Mayatepek E, Meissner T, Stožer A, Lammert E. Scholz O, et al. Among authors: hamacher a. Cell Chem Biol. 2021 Oct 21;28(10):1474-1488.e7. doi: 10.1016/j.chembiol.2021.05.011. Epub 2021 Jun 11. Cell Chem Biol. 2021. PMID: 34118188 Free article.
68 results