Kostenis E - Search Results

1

The Bacterial G_q Signal Transduction Inhibitor FR900359 Impairs Soil-Associated Nematodes.

Hanke W, Alenfelder J, Liu J, Gutbrod P, Kehraus S, Crüsemann M, Dörmann P, Kostenis E, Scholz M, König GM. Hanke W, et al. Among authors: kostenis e. J Chem Ecol. 2023 Oct;49(9-10):549-569. doi: 10.1007/s10886-023-01442-1. Epub 2023 Jul 15. J Chem Ecol. 2023. PMID: 37453001 Free PMC article.

2

Oxytocin-Modulated Ion Channel Ensemble Controls Depolarization, Integration and Burst Firing in CA2 Pyramidal Neurons.

Liu JJ, Eyring KW, König GM, Kostenis E, Tsien RW. Liu JJ, et al. Among authors: kostenis e. J Neurosci. 2022 Oct 12;42(41):7707-7720. doi: 10.1523/JNEUROSCI.0921-22.2022. Epub 2022 Sep 8. J Neurosci. 2022. PMID: 36414006 Free PMC article.

3

Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets.

Lorza-Gil E, Kaiser G, Carlein C, Hoffmann MDA, König GM, Haug S, Prates Roma L, Rexen Ulven E, Ulven T, Kostenis E, Birkenfeld AL, Häring HU, Ullrich S, Gerst F. Lorza-Gil E, et al. Among authors: kostenis e. Diabetologia. 2023 Aug;66(8):1501-1515. doi: 10.1007/s00125-023-05932-5. Epub 2023 May 23. Diabetologia. 2023. PMID: 37217659 Free PMC article.

4

Pharmacological Gq inhibition induces strong pulmonary vasorelaxation and reverses pulmonary hypertension.

Seidinger A, Roberts R, Bai Y, Müller M, Pfeil E, Matthey M, Rieck S, Alenfelder J, König GM, Pfeifer A, Kostenis E, Klinke A, Fleischmann BK, Wenzel D. Seidinger A, et al. Among authors: kostenis e. EMBO Mol Med. 2024 Aug;16(8):1930-1956. doi: 10.1038/s44321-024-00096-0. Epub 2024 Jul 8. EMBO Mol Med. 2024. PMID: 38977926 Free PMC article.

5

Intron retention of an adhesion GPCR generates 1TM isoforms required for 7TM-GPCR function.

Bormann A, Körner MB, Dahse AK, Gläser MS, Irmer J, Lede V, Alenfelder J, Lehmann J, Hall DCN, Thane M, Schleyer M, Kostenis E, Schöneberg T, Bigl M, Langenhan T, Ljaschenko D, Scholz N. Bormann A, et al. Among authors: kostenis e. Cell Rep. 2024 Dec 18;44(1):115078. doi: 10.1016/j.celrep.2024.115078. Online ahead of print. Cell Rep. 2024. PMID: 39705141 Free article.

6

Giving ERK a jERK from the endosome.

Kostenis E, Bravo S, Gomeza J. Kostenis E, et al. Trends Pharmacol Sci. 2023 Mar;44(3):131-133. doi: 10.1016/j.tips.2022.12.004. Epub 2023 Jan 3. Trends Pharmacol Sci. 2023. PMID: 36604224

7

Platelet P2Y₁ receptor exhibits constitutive G protein signaling and β-arrestin 2 recruitment.

Ribes A, Garcia C, Gratacap MP, Kostenis E, Martinez LO, Payrastre B, Sénard JM, Galés C, Pons V. Ribes A, et al. Among authors: kostenis e. BMC Biol. 2023 Feb 1;21(1):14. doi: 10.1186/s12915-023-01528-y. BMC Biol. 2023. PMID: 36721118 Free PMC article.

8

Transactivation of Met signaling by oncogenic Gnaq drives the evolution of melanoma in Hgf-Cdk4 mice.

Mengoni M, Braun AD, Seedarala S, Bonifatius S, Kostenis E, Schanze D, Zenker M, Tüting T, Gaffal E. Mengoni M, et al. Among authors: kostenis e. Cancer Gene Ther. 2024 Jun;31(6):884-893. doi: 10.1038/s41417-024-00744-0. Epub 2024 Feb 15. Cancer Gene Ther. 2024. PMID: 38360887 Free PMC article.

9

A human obesity-associated MC4R mutation with defective Gq/11α signaling leads to hyperphagia in mice.

Metzger PJ, Zhang A, Carlson BA, Sun H, Cui Z, Li Y, Jahnke MT, Layton DR, Gupta MB, Liu N, Kostenis E, Gavrilova O, Chen M, Weinstein LS. Metzger PJ, et al. Among authors: kostenis e. J Clin Invest. 2024 Jan 4;134(4):e165418. doi: 10.1172/JCI165418. J Clin Invest. 2024. PMID: 38175730 Free PMC article.

10

Label-free biosensor assay decodes the dynamics of Toll-like receptor signaling.

Holze J, Lauber F, Soler S, Kostenis E, Weindl G. Holze J, et al. Among authors: kostenis e. Nat Commun. 2024 Nov 12;15(1):9554. doi: 10.1038/s41467-024-53770-9. Nat Commun. 2024. PMID: 39532846 Free PMC article.

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