Martinic MM - Search Results

1

Combination treatment of a novel CXCR3 antagonist ACT-777991 with an anti-CD3 antibody synergistically increases persistent remission in experimental models of type 1 diabetes.

Christen U, Pouzol L, Tunis M, Sassi A, Tondello C, Bayer M, Hintermann E, Strasser DS, Schuldes S, Mentzel U, Martinic MM. Christen U, et al. Among authors: martinic mm. Clin Exp Immunol. 2023 Dec 12;214(2):131-143. doi: 10.1093/cei/uxad083. Clin Exp Immunol. 2023. PMID: 37458220 Free PMC article.

2

Discovery of Clinical Candidate ACT-777991, a Potent CXCR3 Antagonist for Antigen-Driven and Inflammatory Pathologies.

Meyer EA, Äänismaa P, Ertel EA, Hühn E, Strasser DS, Rey M, Murphy MJ, Martinic MM, Pouzol L, Froidevaux S, Keller MP, Caroff E. Meyer EA, et al. Among authors: martinic mm. J Med Chem. 2023 Mar 23;66(6):4179-4196. doi: 10.1021/acs.jmedchem.3c00074. Epub 2023 Mar 8. J Med Chem. 2023. PMID: 36883854

3

ACKR3 Antagonism Enhances the Repair of Demyelinated Lesions Through Both Immunomodulatory and Remyelinating Effects.

Pouzol L, Sassi A, Tunis M, Zurbach A, Baumlin N, Gnerre C, Strasser DS, Marrie J, Vezzali E, Martinic MM. Pouzol L, et al. Among authors: martinic mm. Neurochem Res. 2024 Aug;49(8):2087-2104. doi: 10.1007/s11064-024-04173-1. Epub 2024 May 31. Neurochem Res. 2024. PMID: 38819698 Free PMC article.

4

Cenerimod, a selective S1P₁ receptor modulator, improves organ-specific disease outcomes in animal models of Sjögren's syndrome.

Gerossier E, Nayar S, Froidevaux S, Smith CG, Runser C, Iannizzotto V, Vezzali E, Pierlot G, Mentzel U, Murphy MJ, Martinic MM, Barone F. Gerossier E, et al. Among authors: martinic mm. Arthritis Res Ther. 2021 Nov 29;23(1):289. doi: 10.1186/s13075-021-02673-x. Arthritis Res Ther. 2021. PMID: 34839819 Free PMC article.

5

CXCR7 Antagonism Reduces Acute Lung Injury Pathogenesis.

Pouzol L, Sassi A, Baumlin N, Tunis M, Strasser DS, Lehembre F, Martinic MM. Pouzol L, et al. Among authors: martinic mm. Front Pharmacol. 2021 Nov 5;12:748740. doi: 10.3389/fphar.2021.748740. eCollection 2021. Front Pharmacol. 2021. PMID: 34803691 Free PMC article.

6

ACT-1004-1239, a first-in-class CXCR7 antagonist with both immunomodulatory and promyelinating effects for the treatment of inflammatory demyelinating diseases.

Pouzol L, Baumlin N, Sassi A, Tunis M, Marrie J, Vezzali E, Farine H, Mentzel U, Martinic MM. Pouzol L, et al. Among authors: martinic mm. FASEB J. 2021 Mar;35(3):e21431. doi: 10.1096/fj.202002465R. FASEB J. 2021. PMID: 33595155

7

Preclinical to clinical translation of cenerimod, a novel S1P₁ receptor modulator, in systemic lupus erythematosus.

Strasser DS, Froidevaux S, Sippel V, Gerossier E, Grieder U, Pierlot GM, Kieninger-Graefitsch A, Vezzali E, Stalder AK, Renault B, Ryge J, Hart A, Mentzel U, Groenen PMA, Keller MP, Trendelenburg M, Martinic MM, Murphy MJ. Strasser DS, et al. Among authors: martinic mm. RMD Open. 2020 Sep;6(2):e001261. doi: 10.1136/rmdopen-2020-001261. RMD Open. 2020. PMID: 32917831 Free PMC article.

8

Therapeutic Potential of Ponesimod Alone and in Combination with Dimethyl Fumarate in Experimental Models of Multiple Sclerosis.

Pouzol L, Piali L, Bernard CC, Martinic MM, Steiner B, Clozel M. Pouzol L, et al. Among authors: martinic mm. Innov Clin Neurosci. 2019 Mar 1;16(3-4):22-30. Innov Clin Neurosci. 2019. PMID: 31214480 Free PMC article.

9

The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8⁺ Thymocyte Selection.

Martinic MM, Caminschi I, O'Keeffe M, Thinnes TC, Grumont R, Gerondakis S, McKay DB, Nemazee D, Gavin AL. Martinic MM, et al. J Immunol. 2017 Apr 1;198(7):2649-2660. doi: 10.4049/jimmunol.1601462. Epub 2017 Feb 15. J Immunol. 2017. PMID: 28202617 Free PMC article.

10

A novel technique for the in vivo imaging of autoimmune diabetes development in the pancreas by two-photon microscopy.

Coppieters K, Martinic MM, Kiosses WB, Amirian N, von Herrath M. Coppieters K, et al. Among authors: martinic mm. PLoS One. 2010 Dec 23;5(12):e15732. doi: 10.1371/journal.pone.0015732. PLoS One. 2010. PMID: 21203413 Free PMC article.

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