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Combination treatment of a novel CXCR3 antagonist ACT-777991 with an anti-CD3 antibody synergistically increases persistent remission in experimental models of type 1 diabetes.
Christen U, Pouzol L, Tunis M, Sassi A, Tondello C, Bayer M, Hintermann E, Strasser DS, Schuldes S, Mentzel U, Martinic MM. Christen U, et al. Among authors: schuldes s. Clin Exp Immunol. 2023 Dec 12;214(2):131-143. doi: 10.1093/cei/uxad083. Clin Exp Immunol. 2023. PMID: 37458220 Free PMC article.