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Gene-expression profiling of laser-dissected islets and studies in deficient mice reveal chemokines as differential driving force of type 1 diabetes.
Bender C, Müller P, Tondello C, Horn J, Holdener M, Lasch S, Bayer M, Pfeilschifter JM, Tacke F, Ludwig A, Hansmann ML, Döring C, Hintermann E, Christen U. Bender C, et al. Among authors: tondello c. J Autoimmun. 2024 Feb;143:103161. doi: 10.1016/j.jaut.2023.103161. Epub 2023 Dec 22. J Autoimmun. 2024. PMID: 38141419
Combination treatment of a novel CXCR3 antagonist ACT-777991 with an anti-CD3 antibody synergistically increases persistent remission in experimental models of type 1 diabetes.
Christen U, Pouzol L, Tunis M, Sassi A, Tondello C, Bayer M, Hintermann E, Strasser DS, Schuldes S, Mentzel U, Martinic MM. Christen U, et al. Among authors: tondello c. Clin Exp Immunol. 2023 Dec 12;214(2):131-143. doi: 10.1093/cei/uxad083. Clin Exp Immunol. 2023. PMID: 37458220 Free PMC article.
Dexamethasone Conjugation to Biodegradable Avidin-Nucleic-Acid-Nano-Assemblies Promotes Selective Liver Targeting and Improves Therapeutic Efficacy in an Autoimmune Hepatitis Murine Model.
Violatto MB, Casarin E, Talamini L, Russo L, Baldan S, Tondello C, Messmer M, Hintermann E, Rossi A, Passoni A, Bagnati R, Biffi S, Toffanin C, Gimondi S, Fumagalli S, De Simoni MG, Barisani D, Salmona M, Christen U, Invernizzi P, Bigini P, Morpurgo M. Violatto MB, et al. Among authors: tondello c. ACS Nano. 2019 Apr 23;13(4):4410-4423. doi: 10.1021/acsnano.8b09655. Epub 2019 Mar 18. ACS Nano. 2019. PMID: 30883091