Huang JW - Search Results

1

Mechanism of DNA unwinding by hexameric MCM8-9 in complex with HROB.

Acharya A, Bret H, Huang JW, Mütze M, Göse M, Kissling V, Seidel R, Ciccia A, Guérois R, Cejka P. Acharya A, et al. Among authors: huang jw. Res Sq [Preprint]. 2023 Jun 26:rs.3.rs-3054483. doi: 10.21203/rs.3.rs-3054483/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Apr 27;15(1):3584. doi: 10.1038/s41467-024-47936-8 PMID: 37461676 Free PMC article. Updated. Preprint.

2

Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response.

Ciccia A, Huang JW, Izhar L, Sowa ME, Harper JW, Elledge SJ. Ciccia A, et al. Among authors: huang jw. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18631-6. doi: 10.1073/pnas.1422488112. Epub 2014 Dec 15. Proc Natl Acad Sci U S A. 2014. PMID: 25512513 Free PMC article.

3

Replication Fork Slowing and Reversal upon DNA Damage Require PCNA Polyubiquitination and ZRANB3 DNA Translocase Activity.

Vujanovic M, Krietsch J, Raso MC, Terraneo N, Zellweger R, Schmid JA, Taglialatela A, Huang JW, Holland CL, Zwicky K, Herrador R, Jacobs H, Cortez D, Ciccia A, Penengo L, Lopes M. Vujanovic M, et al. Among authors: huang jw. Mol Cell. 2017 Sep 7;67(5):882-890.e5. doi: 10.1016/j.molcel.2017.08.010. Mol Cell. 2017. PMID: 28886337 Free PMC article.

4

Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers.

Taglialatela A, Alvarez S, Leuzzi G, Sannino V, Ranjha L, Huang JW, Madubata C, Anand R, Levy B, Rabadan R, Cejka P, Costanzo V, Ciccia A. Taglialatela A, et al. Among authors: huang jw. Mol Cell. 2017 Oct 19;68(2):414-430.e8. doi: 10.1016/j.molcel.2017.09.036. Mol Cell. 2017. PMID: 29053959 Free PMC article.

5

Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant.

Nambiar TS, Billon P, Diedenhofen G, Hayward SB, Taglialatela A, Cai K, Huang JW, Leuzzi G, Cuella-Martin R, Palacios A, Gupta A, Egli D, Ciccia A. Nambiar TS, et al. Among authors: huang jw. Nat Commun. 2019 Jul 30;10(1):3395. doi: 10.1038/s41467-019-11105-z. Nat Commun. 2019. PMID: 31363085 Free PMC article.

6

MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage.

Huang JW, Acharya A, Taglialatela A, Nambiar TS, Cuella-Martin R, Leuzzi G, Hayward SB, Joseph SA, Brunette GJ, Anand R, Soni RK, Clark NL, Bernstein KA, Cejka P, Ciccia A. Huang JW, et al. Nat Commun. 2020 Jun 11;11(1):2948. doi: 10.1038/s41467-020-16718-3. Nat Commun. 2020. PMID: 32528060 Free PMC article.

7

Time for remodeling: SNF2-family DNA translocases in replication fork metabolism and human disease.

Joseph SA, Taglialatela A, Leuzzi G, Huang JW, Cuella-Martin R, Ciccia A. Joseph SA, et al. Among authors: huang jw. DNA Repair (Amst). 2020 Nov;95:102943. doi: 10.1016/j.dnarep.2020.102943. Epub 2020 Aug 15. DNA Repair (Amst). 2020. PMID: 32971328 Free PMC article. Review.

8

Functional interrogation of DNA damage response variants with base editing screens.

Cuella-Martin R, Hayward SB, Fan X, Chen X, Huang JW, Taglialatela A, Leuzzi G, Zhao J, Rabadan R, Lu C, Shen Y, Ciccia A. Cuella-Martin R, et al. Among authors: huang jw. Cell. 2021 Feb 18;184(4):1081-1097.e19. doi: 10.1016/j.cell.2021.01.041. Cell. 2021. PMID: 33606978 Free PMC article.

9

REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps.

Taglialatela A, Leuzzi G, Sannino V, Cuella-Martin R, Huang JW, Wu-Baer F, Baer R, Costanzo V, Ciccia A. Taglialatela A, et al. Among authors: huang jw. Mol Cell. 2021 Oct 7;81(19):4008-4025.e7. doi: 10.1016/j.molcel.2021.08.016. Epub 2021 Sep 10. Mol Cell. 2021. PMID: 34508659 Free PMC article.

10

Mechanism of DNA unwinding by hexameric MCM8-9 in complex with HROB.

Acharya A, Bret H, Huang JW, Mütze M, Göse M, Kissling V, Seidel R, Ciccia A, Guérois R, Cejka P. Acharya A, et al. Among authors: huang jw. bioRxiv [Preprint]. 2023 Jun 12:2023.06.12.544631. doi: 10.1101/2023.06.12.544631. bioRxiv. 2023. Update in: Nat Commun. 2024 Apr 27;15(1):3584. doi: 10.1038/s41467-024-47936-8 PMID: 37398313 Free PMC article. Updated. Preprint.

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