Zhang Z - Search Results

1

Fully Automated Radiosynthesis of [¹⁸F]mG4P027 for mGluR4 Imaging.

Moon SH, El Fakhri G, Zhang Z, Brownell AL, Wang J. Moon SH, et al. Among authors: zhang z. iRadiology. 2023 Jun;1(2):120-127. doi: 10.1002/ird3.25. Epub 2023 Jun 20. iRadiology. 2023. PMID: 37496513 Free PMC article.

2

Detailed radiosynthesis of [¹⁸ F]mG4P027 as a positron emission tomography radiotracer for mGluR4.

Wang J, Moon SH, Cleary MB, Shoup TM, El Fakhri G, Zhang Z, Brownell AL. Wang J, et al. Among authors: zhang z. J Labelled Comp Radiopharm. 2023 Feb;66(2):34-40. doi: 10.1002/jlcr.4011. Epub 2023 Jan 19. J Labelled Comp Radiopharm. 2023. PMID: 36593743 Free PMC article.

3

Radiosynthesis of PET radiotracer as a prodrug for imaging group II metabotropic glutamate receptors in vivo.

Wang JQ, Zhang Z, Kuruppu D, Brownell AL. Wang JQ, et al. Among authors: zhang z. Bioorg Med Chem Lett. 2012 Mar 1;22(5):1958-62. doi: 10.1016/j.bmcl.2012.01.039. Epub 2012 Jan 21. Bioorg Med Chem Lett. 2012. PMID: 22318160 Free PMC article.

4

Radiosynthesis of N-(4-chloro-3-[(11)C]methoxyphenyl)-2-picolinamide ([(11)C]ML128) as a PET radiotracer for metabotropic glutamate receptor subtype 4 (mGlu4).

Kil KE, Zhang Z, Jokivarsi K, Gong C, Choi JK, Kura S, Brownell AL. Kil KE, et al. Among authors: zhang z. Bioorg Med Chem. 2013 Oct 1;21(19):5955-62. doi: 10.1016/j.bmc.2013.07.046. Epub 2013 Aug 2. Bioorg Med Chem. 2013. PMID: 23978356 Free PMC article.

5

Radiosynthesis and evaluation of an 18F-labeled positron emission tomography (PET) radioligand for metabotropic glutamate receptor subtype 4 (mGlu4).

Kil KE, Poutiainen P, Zhang Z, Zhu A, Choi JK, Jokivarsi K, Brownell AL. Kil KE, et al. Among authors: zhang z. J Med Chem. 2014 Nov 13;57(21):9130-8. doi: 10.1021/jm501245b. Epub 2014 Oct 27. J Med Chem. 2014. PMID: 25330258 Free PMC article.

6

Synthesis and Characterization of Fluorine-18-Labeled N-(4-Chloro-3-((fluoromethyl-d₂)thio)phenyl)picolinamide for Imaging of mGluR4 in Brain.

Wang J, Qu X, Shoup TM, Yuan G, Afshar S, Pan C, Zhu A, Choi JK, Kang HJ, Poutiainen P, El Fakhri G, Zhang Z, Brownell AL. Wang J, et al. Among authors: zhang z. J Med Chem. 2020 Mar 26;63(6):3381-3389. doi: 10.1021/acs.jmedchem.0c00201. Epub 2020 Mar 4. J Med Chem. 2020. PMID: 32081008 Free PMC article.

7

Improved Synthesis of the Thiophenol Precursor N-(4-Chloro-3-mercaptophenyl)picolinamide for Making the mGluR4 PET Ligand.

Wang J, Shoup TM, Brownell AL, Zhang Z. Wang J, et al. Among authors: zhang z. Tetrahedron. 2019 Jul 19;75(29):3917-3922. doi: 10.1016/j.tet.2019.06.010. Epub 2019 Jun 6. Tetrahedron. 2019. PMID: 32831413 Free PMC article.

8

Design, Synthesis, and Characterization of Benzimidazole Derivatives as Positron Emission Tomography Imaging Ligands for Metabotropic Glutamate Receptor 2.

Yuan G, Qu X, Zheng B, Neelamegam R, Afshar S, Iyengar S, Pan C, Wang J, Kang HJ, Ondrechen MJ, Poutiainen P, El Fakhri G, Zhang Z, Brownell AL. Yuan G, et al. Among authors: zhang z. J Med Chem. 2020 Oct 22;63(20):12060-12072. doi: 10.1021/acs.jmedchem.0c01394. Epub 2020 Oct 7. J Med Chem. 2020. PMID: 32981322 Free PMC article.

9

Synthesis and Characterization of [¹⁸F]JNJ-46356479 as the First ¹⁸F-Labeled PET Imaging Ligand for Metabotropic Glutamate Receptor 2.

Yuan G, Guehl NJ, Zheng B, Qu X, Moon SH, Dhaynaut M, Shoup TM, Afshar S, Kang HJ, Zhang Z, El Fakhri G, Normandin MD, Brownell AL. Yuan G, et al. Among authors: zhang z. Mol Imaging Biol. 2021 Aug;23(4):527-536. doi: 10.1007/s11307-021-01586-0. Epub 2021 Feb 8. Mol Imaging Biol. 2021. PMID: 33559035 Free PMC article.

10

Organomediated cleavage of benzoyl group enables an efficient synthesis of 1-(6-nitropyridin-2-yl)thiourea and its application for developing ¹⁸F-labeled PET tracers.

Wang J, Takahashi K, Shoup TM, Gong L, Li Y, El Fakhri G, Zhang Z, Brownell AL. Wang J, et al. Among authors: zhang z. Bioorg Chem. 2022 Jul;124:105804. doi: 10.1016/j.bioorg.2022.105804. Epub 2022 Apr 12. Bioorg Chem. 2022. PMID: 35468416 Free PMC article.

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