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First fragment-based screening identifies new chemotypes inhibiting ERAP1-metalloprotease.
Fougiaxis V, Barcherini V, Petrovic MM, Sierocki P, Warenghem S, Leroux F, Bou Karroum N, Petit-Cancelier F, Rodeschini V, Roche D, Deprez B, Deprez-Poulain R. Fougiaxis V, et al. Among authors: leroux f. Eur J Med Chem. 2024 Dec 15;280:116926. doi: 10.1016/j.ejmech.2024.116926. Epub 2024 Sep 30. Eur J Med Chem. 2024. PMID: 39369482 Free article.
Phenylseleno trifluoromethoxylation of alkenes.
Delobel C, Panossian A, Hanquet G, Leroux FR, Toulgoat F, Billard T. Delobel C, et al. Among authors: leroux fr. Beilstein J Org Chem. 2024 Sep 26;20:2434-2441. doi: 10.3762/bjoc.20.207. eCollection 2024. Beilstein J Org Chem. 2024. PMID: 39355857 Free PMC article.
N-acylbenzimidazoles as selective Acylators of the catalytic cystein of the coronavirus 3CL protease.
Chaibi FZ, Brier L, Carré P, Landry V, Desmarets L, Tarricone A, Cantrelle FX, Moschidi D, Herledan A, Biela A, Bourgeois F, Ribes C, Ikherbane S, Malessan M, Dubuisson J, Belouzard S, Hanoulle X, Leroux F, Deprez B, Charton J. Chaibi FZ, et al. Among authors: leroux f. Eur J Med Chem. 2024 Oct 5;276:116707. doi: 10.1016/j.ejmech.2024.116707. Epub 2024 Jul 24. Eur J Med Chem. 2024. PMID: 39068863
230 results