Harischandra DS - Search Results

1

TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease.

Zhang ZY, Harischandra DS, Wang R, Ghaisas S, Zhao JY, McMonagle TP, Zhu G, Lacuarta KD, Song J, Trojanowski JQ, Xu H, Lee VM, Yang X. Zhang ZY, et al. Among authors: harischandra ds. Science. 2023 Jul 28;381(6656):eadd6696. doi: 10.1126/science.add6696. Epub 2023 Jul 28. Science. 2023. PMID: 37499037 Free PMC article.

2

TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson's Disease.

Zhu G, Harischandra DS, Ghaisas S, Zhang P, Prall W, Huang L, Maghames C, Guo L, Luna E, Mack KL, Torrente MP, Luk KC, Shorter J, Yang X. Zhu G, et al. Among authors: harischandra ds. Cell Rep. 2020 Dec 1;33(9):108418. doi: 10.1016/j.celrep.2020.108418. Cell Rep. 2020. PMID: 33264628 Free PMC article.

3

Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein.

Harischandra DS, Rokad D, Neal ML, Ghaisas S, Manne S, Sarkar S, Panicker N, Zenitsky G, Jin H, Lewis M, Huang X, Anantharam V, Kanthasamy A, Kanthasamy AG. Harischandra DS, et al. Sci Signal. 2019 Mar 12;12(572):eaau4543. doi: 10.1126/scisignal.aau4543. Sci Signal. 2019. PMID: 30862700 Free PMC article.

4

Exosomes in Toxicology: Relevance to Chemical Exposure and Pathogenesis of Environmentally Linked Diseases.

Harischandra DS, Ghaisas S, Rokad D, Kanthasamy AG. Harischandra DS, et al. Toxicol Sci. 2017 Jul 1;158(1):3-13. doi: 10.1093/toxsci/kfx074. Toxicol Sci. 2017. PMID: 28505322 Free PMC article. Review.

5

Role of neurotoxicants and traumatic brain injury in α-synuclein protein misfolding and aggregation.

Rokad D, Ghaisas S, Harischandra DS, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG. Rokad D, et al. Among authors: harischandra ds. Brain Res Bull. 2017 Jul;133:60-70. doi: 10.1016/j.brainresbull.2016.12.003. Epub 2016 Dec 16. Brain Res Bull. 2017. PMID: 27993598 Free PMC article.

6

Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation.

Harischandra DS, Ghaisas S, Zenitsky G, Jin H, Kanthasamy A, Anantharam V, Kanthasamy AG. Harischandra DS, et al. Front Neurosci. 2019 Jun 26;13:654. doi: 10.3389/fnins.2019.00654. eCollection 2019. Front Neurosci. 2019. PMID: 31293375 Free PMC article. Review.

7

Neuronal protection against oxidative insult by polyanhydride nanoparticle-based mitochondria-targeted antioxidant therapy.

Brenza TM, Ghaisas S, Ramirez JEV, Harischandra D, Anantharam V, Kalyanaraman B, Kanthasamy AG, Narasimhan B. Brenza TM, et al. Nanomedicine. 2017 Apr;13(3):809-820. doi: 10.1016/j.nano.2016.10.004. Epub 2016 Oct 19. Nanomedicine. 2017. PMID: 27771430 Free PMC article.

8

Environmental neurotoxicant manganese regulates exosome-mediated extracellular miRNAs in cell culture model of Parkinson's disease: Relevance to α-synuclein misfolding in metal neurotoxicity.

Harischandra DS, Ghaisas S, Rokad D, Zamanian M, Jin H, Anantharam V, Kimber M, Kanthasamy A, Kanthasamy AG. Harischandra DS, et al. Neurotoxicology. 2018 Jan;64:267-277. doi: 10.1016/j.neuro.2017.04.007. Epub 2017 Apr 24. Neurotoxicology. 2018. PMID: 28450057 Free PMC article.

9

Enhanced differentiation of human dopaminergic neuronal cell model for preclinical translational research in Parkinson's disease.

Harischandra DS, Rokad D, Ghaisas S, Verma S, Robertson A, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG. Harischandra DS, et al. Biochim Biophys Acta Mol Basis Dis. 2020 Apr 1;1866(4):165533. doi: 10.1016/j.bbadis.2019.165533. Epub 2019 Aug 20. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 31442530 Free PMC article.

10

Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia.

Panicker N, Sarkar S, Harischandra DS, Neal M, Kam TI, Jin H, Saminathan H, Langley M, Charli A, Samidurai M, Rokad D, Ghaisas S, Pletnikova O, Dawson VL, Dawson TM, Anantharam V, Kanthasamy AG, Kanthasamy A. Panicker N, et al. Among authors: harischandra ds. J Exp Med. 2019 Jun 3;216(6):1411-1430. doi: 10.1084/jem.20182191. Epub 2019 Apr 29. J Exp Med. 2019. PMID: 31036561 Free PMC article.

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