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Page 1
Distinct ways of G:U recognition by conserved tRNA binding motifs.
Chong YE, Guo M, Yang XL, Kuhle B, Naganuma M, Sekine SI, Yokoyama S, Schimmel P. Chong YE, et al. Among authors: kuhle b. Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):7527-7532. doi: 10.1073/pnas.1807109115. Epub 2018 Jul 2. Proc Natl Acad Sci U S A. 2018. PMID: 29967150 Free PMC article.
CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells.
Blocquel D, Sun L, Matuszek Z, Li S, Weber T, Kuhle B, Kooi G, Wei N, Baets J, Pan T, Schimmel P, Yang XL. Blocquel D, et al. Among authors: kuhle b. Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19440-19448. doi: 10.1073/pnas.1908288116. Epub 2019 Sep 9. Proc Natl Acad Sci U S A. 2019. PMID: 31501329 Free PMC article.
CMT2N-causing aminoacylation domain mutants enable Nrp1 interaction with AlaRS.
Sun L, Wei N, Kuhle B, Blocquel D, Novick S, Matuszek Z, Zhou H, He W, Zhang J, Weber T, Horvath R, Latour P, Pan T, Schimmel P, Griffin PR, Yang XL. Sun L, et al. Among authors: kuhle b. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2012898118. doi: 10.1073/pnas.2012898118. Proc Natl Acad Sci U S A. 2021. PMID: 33753480 Free PMC article.
tRNA renovatio: Rebirth through fragmentation.
Kuhle B, Chen Q, Schimmel P. Kuhle B, et al. Mol Cell. 2023 Nov 16;83(22):3953-3971. doi: 10.1016/j.molcel.2023.09.016. Epub 2023 Oct 5. Mol Cell. 2023. PMID: 37802077 Free PMC article. Review.
26 results