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Optimization of an adverse outcome pathway network on chemical-induced cholestasis using an artificial intelligence-assisted data collection and confidence level quantification approach.
van Ertvelde J, Verhoeven A, Maerten A, Cooreman A, Santos Rodrigues BD, Sanz-Serrano J, Mihajlovic M, Tripodi I, Teunis M, Jover R, Luechtefeld T, Vanhaecke T, Jiang J, Vinken M. van Ertvelde J, et al. J Biomed Inform. 2023 Sep;145:104465. doi: 10.1016/j.jbi.2023.104465. Epub 2023 Aug 2. J Biomed Inform. 2023. PMID: 37541407 Free article.
A quantitative weight-of-evidence method for confidence assessment of adverse outcome pathway networks: A case study on chemical-induced liver steatosis.
Verhoeven A, van Ertvelde J, Boeckmans J, Gatzios A, Jover R, Lindeman B, Lopez-Soop G, Rodrigues RM, Rapisarda A, Sanz-Serrano J, Stinckens M, Sepehri S, Teunis M, Vinken M, Jiang J, Vanhaecke T. Verhoeven A, et al. Among authors: van ertvelde j. Toxicology. 2024 Jun;505:153814. doi: 10.1016/j.tox.2024.153814. Epub 2024 Apr 25. Toxicology. 2024. PMID: 38677583