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Page 1
Effects of chemoradiotherapy on surface PD-L1 expression in esophageal cancer and its implications for immunotherapy.
Hampe L, Küffer S, Niemeier T, Scheele NC, Hampe LZ, Riedl AL, Fischer LA, Ziegler DA, Leu M, Dröge LH, König A, Ghadimi M, Braulke F, Rieken S, Bohnenberger H, El Shafie RA. Hampe L, et al. Among authors: kuffer s. Front Immunol. 2024 Dec 23;15:1509051. doi: 10.3389/fimmu.2024.1509051. eCollection 2024. Front Immunol. 2024. PMID: 39763660 Free PMC article.
Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response in pancreatic cancer.
Klein L, Tu M, Krebs N, Urbach L, Grimm D, Latif MU, Penz F, Blandau A, Wu X, Samuel RD, Küffer S, Wegwitz F, Chan N, Aliar K, Vyas F, Kishore U, Hessmann E, Trumpp A, Espinet E, Papantonis A, Khokha R, Ellenrieder V, Grünwald BT, Singh SK. Klein L, et al. Among authors: kuffer s. Nat Commun. 2025 Jan 6;16(1):335. doi: 10.1038/s41467-024-55330-7. Nat Commun. 2025. PMID: 39762215 Free PMC article.
Immunohistochemistry for YAP1 N-terminus and C-terminus highlights metaplastic thymoma and high-grade thymic epithelial tumors by different staining patterns.
Yamada Y, Küffer S, Sauer C, Hoki M, Shibuya S, Tsujii H, Ono K, Moriyoshi K, Date H, Yoshizawa A, Szolkowska M, Haga H, Ströbel P, Marx A. Yamada Y, et al. Among authors: kuffer s. Virchows Arch. 2024 Sep;485(3):461-469. doi: 10.1007/s00428-024-03888-4. Epub 2024 Aug 3. Virchows Arch. 2024. PMID: 39096416
Non-Mutational Key Features in the Biology of Thymomas.
Küffer S, Müller D, Marx A, Ströbel P. Küffer S, et al. Cancers (Basel). 2024 Feb 26;16(5):942. doi: 10.3390/cancers16050942. Cancers (Basel). 2024. PMID: 38473304 Free PMC article. Review.
Characterizing the mutational burden, DNA methylation landscape, and proteome of germ cell tumor-related somatic-type malignancies to identify the tissue-of-origin, mechanisms of therapy resistance, and druggable targets.
Bremmer F, Pongratanakul P, Skowron M, Che Y, Richter A, Küffer S, Reuter-Jessen K, Bohnenberger H, Pauls S, Kresbach C, Schüller U, Stühler K, Ströbel P, Albers P, Nettersheim D. Bremmer F, et al. Among authors: kuffer s. Br J Cancer. 2023 Nov;129(10):1580-1589. doi: 10.1038/s41416-023-02425-5. Epub 2023 Sep 19. Br J Cancer. 2023. PMID: 37726478 Free PMC article.
Proteomic analysis identifies argininosuccinate synthetase 1 and special AT-rich sequence binding protein 1 as reliable markers for the immunohistochemical distinction between WHO types A and B3 thymomas.
Bremmer F, Bohnenberger H, Findeisen P, Welter S, von Hammerstein-Equord A, Hinterthaner M, Müller D, Küffer S, Okada S, Marx A, Ströbel P. Bremmer F, et al. Among authors: kuffer s. Histopathology. 2023 Oct;83(4):607-616. doi: 10.1111/his.14972. Epub 2023 Jun 12. Histopathology. 2023. PMID: 37308176
Targeting CLDN6 in germ cell tumors by an antibody-drug-conjugate and studying therapy resistance of yolk-sac tumors to identify and screen specific therapeutic options.
Skowron MA, Kotthoff M, Bremmer F, Ruhnke K, Parmaksiz F, Richter A, Küffer S, Reuter-Jessen K, Pauls S, Stefanski A, Ströbel P, Stühler K, Nettersheim D. Skowron MA, et al. Among authors: kuffer s. Mol Med. 2023 Mar 29;29(1):40. doi: 10.1186/s10020-023-00636-3. Mol Med. 2023. PMID: 36991316 Free PMC article.
50 results