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Intestinal IL-1β Plays a Role in Protecting against SARS-CoV-2 Infection.
Lücke J, Heinrich F, Malsy J, Meins N, Schnell J, Böttcher M, Nawrocki M, Zhang T, Bertram F, Sabihi M, Kempski J, Blankenburg T, Duprée A, Reeh M, Wolter S, Mann O, Izbicki JR, Lohse AW, Gagliani N, Lütgehetmann M, Bunders MJ, Altfeld M, Sauter G, Giannou AD, Krasemann S, Ondruschka B, Huber S. Lücke J, et al. Among authors: zhang t. J Immunol. 2023 Sep 15;211(6):1052-1061. doi: 10.4049/jimmunol.2200844. J Immunol. 2023. PMID: 37556130 Free PMC article.
Efferocytosis fuels malignant pleural effusion through TIMP1.
Zhao L, Giannou AD, Xu Y, Shiri AM, Liebold I, Steglich B, Bedke T, Zhang T, Lücke J, Scognamiglio P, Kempski J, Woestemeier A, Chen J, Agalioti T, Zazara DE, Lindner D, Janning M, Hennigs JK, Jagirdar RM, Kotsiou OS, Zarogiannis SG, Kobayashi Y, Izbicki JR, Ghosh S, Rothlin CV, Bosurgi L, Huber S, Gagliani N. Zhao L, et al. Among authors: zhang t. Sci Adv. 2021 Aug 13;7(33):eabd6734. doi: 10.1126/sciadv.abd6734. Print 2021 Aug. Sci Adv. 2021. PMID: 34389533 Free PMC article.
Potential role of the bitter taste receptor T2R14 in the prolonged survival and enhanced chemoresponsiveness induced by apigenin.
Stern L, Boehme LF, Goetz MR, Nitschke C, Giannou A, Zhang T, Güngör C, Reeh M, Izbicki JR, Fliegert R, Hausen A, Giese N, Hackert T, Niv MY, Heinrich S, Gaida MM, Ghadban T. Stern L, et al. Among authors: zhang t. Int J Oncol. 2023 Jan;62(1):6. doi: 10.3892/ijo.2022.5454. Epub 2022 Nov 16. Int J Oncol. 2023. PMID: 36382671 Free PMC article.
A Critical Role of the IL-22-IL-22 Binding Protein Axis in Hepatocellular Carcinoma.
Giannou AD, Lücke J, Kleinschmidt D, Shiri AM, Steglich B, Nawrocki M, Zhang T, Zazara DE, Kempski J, Zhao L, Giannou O, Agalioti T, Brockmann L, Bertram F, Sabihi M, Böttcher M, Ewald F, Schulze K, von Felden J, Machicote A, Maroulis IC, Arck PC, Graß JK, Mercanoglu B, Reeh M, Wolter S, Tachezy M, Seese H, Theodorakopoulou M, Lykoudis PM, Heumann A, Uzunoglu FG, Ghadban T, Mann O, Izbicki JR, Li J, Duprée A, Melling N, Gagliani N, Huber S. Giannou AD, et al. Among authors: zhang t. Cancers (Basel). 2022 Dec 7;14(24):6019. doi: 10.3390/cancers14246019. Cancers (Basel). 2022. PMID: 36551508 Free PMC article.
T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis.
Briukhovetska D, Suarez-Gosalvez J, Voigt C, Markota A, Giannou AD, Schübel M, Jobst J, Zhang T, Dörr J, Märkl F, Majed L, Müller PJ, May P, Gottschlich A, Tokarew N, Lücke J, Oner A, Schwerdtfeger M, Andreu-Sanz D, Grünmeier R, Seifert M, Michaelides S, Hristov M, König LM, Cadilha BL, Mikhaylov O, Anders HJ, Rothenfusser S, Flavell RA, Cerezo-Wallis D, Tejedo C, Soengas MS, Bald T, Huber S, Endres S, Kobold S. Briukhovetska D, et al. Among authors: zhang t. Immunity. 2023 Jan 10;56(1):143-161.e11. doi: 10.1016/j.immuni.2022.12.010. Immunity. 2023. PMID: 36630913 Free PMC article.
TNFα aggravates detrimental effects of SARS-CoV-2 infection in the liver.
Lücke J, Nawrocki M, Schnell J, Meins N, Heinrich F, Zhang T, Bertram F, Sabihi M, Böttcher M, Blankenburg T, Pfaff M, Notz S, Kempski J, Reeh M, Wolter S, Mann O, Izbicki JR, Lütgehetmann M, Duprée A, Giannou AD, Ondruschka B, Huber S. Lücke J, et al. Among authors: zhang t. Front Immunol. 2023 Mar 31;14:1151937. doi: 10.3389/fimmu.2023.1151937. eCollection 2023. Front Immunol. 2023. PMID: 37063909 Free PMC article.
IL-22BP controls the progression of liver metastasis in colorectal cancer.
Giannou AD, Kempski J, Zhang T, Lücke J, Shiri AM, Zazara DE, Belios I, Machicote A, Seeger P, Agalioti T, Tintelnot J, Sagebiel A, Tomczak M, Bauditz L, Bedke T, Kocheise L, Mercanoglu B, Fard-Aghaie M, Giorgakis E, Lykoudis PM, Pikouli A, Grass JK, Wahib R, Bardenhagen J, Brunswig B, Heumann A, Ghadban T, Duprée A, Tachezy M, Melling N, Arck PC, Stringa P, Gentilini MV, Gondolesi GE, Nakano R, Thomson AW, Perez D, Li J, Mann O, Izbicki JR, Gagliani N, Maroulis IC, Huber S. Giannou AD, et al. Among authors: zhang t. Front Oncol. 2023 May 31;13:1170502. doi: 10.3389/fonc.2023.1170502. eCollection 2023. Front Oncol. 2023. PMID: 37324022 Free PMC article.
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