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Methylglyoxal down-regulates the expression of cell cycle associated genes and activates the p53 pathway in human umbilical vein endothelial cells.
Braun JD, Pastene DO, Breedijk A, Rodriguez A, Hofmann BB, Sticht C, von Ochsenstein E, Allgayer H, van den Born J, Bakker S, Hauske SJ, Krämer BK, Yard BA, Albrecht T. Braun JD, et al. Among authors: hauske sj. Sci Rep. 2019 Feb 4;9(1):1152. doi: 10.1038/s41598-018-37937-1. Sci Rep. 2019. PMID: 30718683 Free PMC article.
Human carnosinase 1 overexpression aggravates diabetes and renal impairment in BTBROb/Ob mice.
Qiu J, Albrecht T, Zhang S, Hauske SJ, Rodriguez-Niño A, Zhang X, Nosan D, Pastene DO, Sticht C, Delatorre C, van Goor H, Porubsky S, Krämer BK, Yard BA. Qiu J, et al. Among authors: hauske sj. J Mol Med (Berl). 2020 Sep;98(9):1333-1346. doi: 10.1007/s00109-020-01957-0. Epub 2020 Aug 15. J Mol Med (Berl). 2020. PMID: 32803273 Free PMC article.
The CNDP1 (CTG)5 Polymorphism Is Associated with Biopsy-Proven Diabetic Nephropathy, Time on Hemodialysis, and Diabetes Duration.
Albrecht T, Zhang S, Braun JD, Xia L, Rodriquez A, Qiu J, Peters V, Schmitt CP, van den Born J, Bakker SJL, Lammert A, Köppel H, Schnuelle P, Krämer BK, Yard BA, Hauske SJ. Albrecht T, et al. Among authors: hauske sj. J Diabetes Res. 2017;2017:9506730. doi: 10.1155/2017/9506730. Epub 2017 May 3. J Diabetes Res. 2017. PMID: 28553654 Free PMC article.
Identification and characterisation of carnostatine (SAN9812), a potent and selective carnosinase (CN1) inhibitor with in vivo activity.
Qiu J, Hauske SJ, Zhang S, Rodriguez-Niño A, Albrecht T, Pastene DO, van den Born J, van Goor H, Ruf S, Kohlmann M, Teufel M, Krämer BK, Hammes HP, Peters V, Yard BA, Kannt A. Qiu J, et al. Among authors: hauske sj. Amino Acids. 2019 Jan;51(1):7-16. doi: 10.1007/s00726-018-2601-z. Epub 2018 Jun 20. Amino Acids. 2019. PMID: 29922921
Carnosine Attenuates the Development of both Type 2 Diabetes and Diabetic Nephropathy in BTBR ob/ob Mice.
Albrecht T, Schilperoort M, Zhang S, Braun JD, Qiu J, Rodriguez A, Pastene DO, Krämer BK, Köppel H, Baelde H, de Heer E, Anna Altomare A, Regazzoni L, Denisi A, Aldini G, van den Born J, Yard BA, Hauske SJ. Albrecht T, et al. Among authors: hauske sj. Sci Rep. 2017 Mar 10;7:44492. doi: 10.1038/srep44492. Sci Rep. 2017. PMID: 28281693 Free PMC article.
Different conformational forms of serum carnosinase detected by a newly developed sandwich ELISA for the measurements of carnosinase concentrations.
Adelmann K, Frey D, Riedl E, Koeppel H, Pfister F, Peters V, Schmitt CP, Sternik P, Hofmann S, Zentgraf HW, Navis G, van den Born J, Bakker SJ, Krämer BK, Yard BA, Hauske SJ. Adelmann K, et al. Among authors: hauske sj. Amino Acids. 2012 Jul;43(1):143-51. doi: 10.1007/s00726-012-1244-8. Epub 2012 Feb 17. Amino Acids. 2012. PMID: 22349764
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