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Page 1
CTLA-4 blockade induces a microglia-Th1 cell partnership that stimulates microglia phagocytosis and anti-tumor function in glioblastoma.
Chen D, Varanasi SK, Hara T, Traina K, Sun M, McDonald B, Farsakoglu Y, Clanton J, Xu S, Garcia-Rivera L, Mann TH, Du V, Chung HK, Xu Z, Tripple V, Casillas E, Ma S, O'Connor C, Yang Q, Zheng Y, Hunter T, Lemke G, Kaech SM. Chen D, et al. Among authors: varanasi sk. Immunity. 2023 Sep 12;56(9):2086-2104.e8. doi: 10.1016/j.immuni.2023.07.015. Epub 2023 Aug 11. Immunity. 2023. PMID: 37572655 Free article.
Manipulating mitochondrial electron flow enhances tumor immunogenicity.
Mangalhara KC, Varanasi SK, Johnson MA, Burns MJ, Rojas GR, Esparza Moltó PB, Sainz AG, Tadepalle N, Abbott KL, Mendiratta G, Chen D, Farsakoglu Y, Kunchok T, Hoffmann FA, Parisi B, Rincon M, Vander Heiden MG, Bosenberg M, Hargreaves DC, Kaech SM, Shadel GS. Mangalhara KC, et al. Among authors: varanasi sk. Science. 2023 Sep 22;381(6664):1316-1323. doi: 10.1126/science.abq1053. Epub 2023 Sep 21. Science. 2023. PMID: 37733872 Free PMC article.
Multi-Omics Atlas-Assisted Discovery of Transcription Factors for Selective T Cell State Programming.
Chung HK, Liu C, Jambor AN, Riesenberg BP, Sun M, Casillas E, Chick B, Wang J, Ma S, Mcdonald B, He P, Yang Q, Chen T, Varanasi SK, LaPorte M, Mann TH, Chen D, Hoffmann F, Tripple V, Ho J, Cho UH, Modliszewski J, Williams A, Liu L, Wang Y, Hargreaves DC, Thaxton JE, Kaech SM, Wang W. Chung HK, et al. Among authors: varanasi sk. bioRxiv [Preprint]. 2024 Sep 18:2023.01.03.522354. doi: 10.1101/2023.01.03.522354. bioRxiv. 2024. PMID: 36711632 Free PMC article. Preprint.
SnapShot: Cancer immunoediting.
Varanasi SK, Kaech SM, Bui JD. Varanasi SK, et al. Cell. 2022 Oct 13;185(21):4038-4038.e1. doi: 10.1016/j.cell.2022.09.027. Cell. 2022. PMID: 36240741 Free article.
Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors.
Xu S, Chaudhary O, Rodríguez-Morales P, Sun X, Chen D, Zappasodi R, Xu Z, Pinto AFM, Williams A, Schulze I, Farsakoglu Y, Varanasi SK, Low JS, Tang W, Wang H, McDonald B, Tripple V, Downes M, Evans RM, Abumrad NA, Merghoub T, Wolchok JD, Shokhirev MN, Ho PC, Witztum JL, Emu B, Cui G, Kaech SM. Xu S, et al. Among authors: varanasi sk. Immunity. 2021 Jul 13;54(7):1561-1577.e7. doi: 10.1016/j.immuni.2021.05.003. Epub 2021 Jun 7. Immunity. 2021. PMID: 34102100 Free PMC article.
T Cell Metabolism in a State of Flux.
Varanasi SK, Ma S, Kaech SM. Varanasi SK, et al. Immunity. 2019 Nov 19;51(5):783-785. doi: 10.1016/j.immuni.2019.10.012. Immunity. 2019. PMID: 31747577 Free article.
Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence.
Harel M, Ortenberg R, Varanasi SK, Mangalhara KC, Mardamshina M, Markovits E, Baruch EN, Tripple V, Arama-Chayoth M, Greenberg E, Shenoy A, Ayasun R, Knafo N, Xu S, Anafi L, Yanovich-Arad G, Barnabas GD, Ashkenazi S, Besser MJ, Schachter J, Bosenberg M, Shadel GS, Barshack I, Kaech SM, Markel G, Geiger T. Harel M, et al. Among authors: varanasi sk. Cell. 2019 Sep 19;179(1):236-250.e18. doi: 10.1016/j.cell.2019.08.012. Epub 2019 Sep 5. Cell. 2019. PMID: 31495571 Free PMC article.
Macrophage-Mediated Phagocytosis and Dissolution of Amyloid-Like Fibrils in Mice, Monitored by Optical Imaging.
Richey T, Foster JS, Williams AD, Williams AB, Stroh A, Macy S, Wooliver C, Heidel RE, Varanasi SK, Ergen EN, Trent DJ, Kania SA, Kennel SJ, Martin EB, Wall JS. Richey T, et al. Among authors: varanasi sk. Am J Pathol. 2019 May;189(5):989-998. doi: 10.1016/j.ajpath.2019.01.011. Epub 2019 Feb 6. Am J Pathol. 2019. PMID: 30735627 Free PMC article.
21 results