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Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target.
Vande Voorde J, Steven RT, Najumudeen AK, Ford CA, Dexter A, Gonzalez-Fernandez A, Nikula CJ, Xiang Y, Ford L, Maneta Stavrakaki S, Gilroy K, Zeiger LB, Pennel K, Hatthakarnkul P, Elia EA, Nasif A, Murta T, Manoli E, Mason S, Gillespie M, Lannagan TRM, Vlahov N, Ridgway RA, Nixon C, Raven A, Mills M, Athineos D, Kanellos G, Nourse C, Gay DM, Hughes M, Burton A, Yan B, Sellers K, Wu V, De Ridder K, Shokry E, Huerta Uribe A, Clark W, Clark G, Kirschner K, Thienpont B, Li VSW, Maddocks ODK, Barry ST, Goodwin RJA, Kinross J, Edwards J, Yuneva MO, Sumpton D, Takats Z, Campbell AD, Bunch J, Sansom OJ. Vande Voorde J, et al. Among authors: takats z. Nat Metab. 2023 Aug;5(8):1303-1318. doi: 10.1038/s42255-023-00857-0. Epub 2023 Aug 14. Nat Metab. 2023. PMID: 37580540 Free PMC article.
Metabolic phenotyping in clinical and surgical environments.
Nicholson JK, Holmes E, Kinross JM, Darzi AW, Takats Z, Lindon JC. Nicholson JK, et al. Among authors: takats z. Nature. 2012 Nov 15;491(7424):384-92. doi: 10.1038/nature11708. Nature. 2012. PMID: 23151581 Review.
Chemo-informatic strategy for imaging mass spectrometry-based hyperspectral profiling of lipid signatures in colorectal cancer.
Veselkov KA, Mirnezami R, Strittmatter N, Goldin RD, Kinross J, Speller AV, Abramov T, Jones EA, Darzi A, Holmes E, Nicholson JK, Takats Z. Veselkov KA, et al. Among authors: takats z. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1216-21. doi: 10.1073/pnas.1310524111. Epub 2014 Jan 7. Proc Natl Acad Sci U S A. 2014. PMID: 24398526 Free PMC article.
Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo.
Ashton S, Song YH, Nolan J, Cadogan E, Murray J, Odedra R, Foster J, Hall PA, Low S, Taylor P, Ellston R, Polanska UM, Wilson J, Howes C, Smith A, Goodwin RJ, Swales JG, Strittmatter N, Takáts Z, Nilsson A, Andren P, Trueman D, Walker M, Reimer CL, Troiano G, Parsons D, De Witt D, Ashford M, Hrkach J, Zale S, Jewsbury PJ, Barry ST. Ashton S, et al. Among authors: takats z. Sci Transl Med. 2016 Feb 10;8(325):325ra17. doi: 10.1126/scitranslmed.aad2355. Sci Transl Med. 2016. PMID: 26865565 Free article.
Universal Sample Preparation Unlocking Multimodal Molecular Tissue Imaging.
Dannhorn A, Kazanc E, Ling S, Nikula C, Karali E, Serra MP, Vorng JL, Inglese P, Maglennon G, Hamm G, Swales J, Strittmatter N, Barry ST, Sansom OJ, Poulogiannis G, Bunch J, Goodwin RJ, Takats Z. Dannhorn A, et al. Among authors: takats z. Anal Chem. 2020 Aug 18;92(16):11080-11088. doi: 10.1021/acs.analchem.0c00826. Epub 2020 Jul 27. Anal Chem. 2020. PMID: 32519547
224 results