Zhang X - Search Results

1

Mutations in human DNA methyltransferase DNMT1 induce specific genome-wide epigenomic and transcriptomic changes in neurodevelopment.

Davis KN, Qu PP, Ma S, Lin L, Plastini M, Dahl N, Plazzi G, Pizza F, O'Hara R, Wong WH, Hallmayer J, Mignot E, Zhang X, Urban AE. Davis KN, et al. Among authors: zhang x. Hum Mol Genet. 2023 Oct 17;32(21):3105-3120. doi: 10.1093/hmg/ddad123. Hum Mol Genet. 2023. PMID: 37584462 Free PMC article.

2

Network Effects of the 15q13.3 Microdeletion on the Transcriptome and Epigenome in Human-Induced Neurons.

Zhang S, Zhang X, Purmann C, Ma S, Shrestha A, Davis KN, Ho M, Huang Y, Pattni R, Wong WH, Bernstein JA, Hallmayer J, Urban AE. Zhang S, et al. Among authors: zhang x. Biol Psychiatry. 2021 Mar 1;89(5):497-509. doi: 10.1016/j.biopsych.2020.06.021. Epub 2020 Jul 1. Biol Psychiatry. 2021. PMID: 32919612 Free PMC article.

3

Integrated functional genomic analyses of Klinefelter and Turner syndromes reveal global network effects of altered X chromosome dosage.

Zhang X, Hong D, Ma S, Ward T, Ho M, Pattni R, Duren Z, Stankov A, Bade Shrestha S, Hallmayer J, Wong WH, Reiss AL, Urban AE. Zhang X, et al. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):4864-4873. doi: 10.1073/pnas.1910003117. Epub 2020 Feb 18. Proc Natl Acad Sci U S A. 2020. PMID: 32071206 Free PMC article.

4

Whole-genome sequencing analysis of CNV using low-coverage and paired-end strategies is efficient and outperforms array-based CNV analysis.

Zhou B, Ho SS, Zhang X, Pattni R, Haraksingh RR, Urban AE. Zhou B, et al. Among authors: zhang x. J Med Genet. 2018 Nov;55(11):735-743. doi: 10.1136/jmedgenet-2018-105272. Epub 2018 Jul 30. J Med Genet. 2018. PMID: 30061371 Free PMC article.

5

Haplotype-resolved and integrated genome analysis of the cancer cell line HepG2.

Zhou B, Ho SS, Greer SU, Spies N, Bell JM, Zhang X, Zhu X, Arthur JG, Byeon S, Pattni R, Saha I, Huang Y, Song G, Perrin D, Wong WH, Ji HP, Abyzov A, Urban AE. Zhou B, et al. Among authors: zhang x. Nucleic Acids Res. 2019 May 7;47(8):3846-3861. doi: 10.1093/nar/gkz169. Nucleic Acids Res. 2019. PMID: 30864654 Free PMC article.

6

Comprehensive, integrated, and phased whole-genome analysis of the primary ENCODE cell line K562.

Zhou B, Ho SS, Greer SU, Zhu X, Bell JM, Arthur JG, Spies N, Zhang X, Byeon S, Pattni R, Ben-Efraim N, Haney MS, Haraksingh RR, Song G, Ji HP, Perrin D, Wong WH, Abyzov A, Urban AE. Zhou B, et al. Among authors: zhang x. Genome Res. 2019 Mar;29(3):472-484. doi: 10.1101/gr.234948.118. Epub 2019 Feb 8. Genome Res. 2019. PMID: 30737237 Free PMC article.

7

Maternal attachment insecurity, maltreatment history, and depressive symptoms are associated with broad DNA methylation signatures in infants.

Robakis TK, Roth MC, King LS, Humphreys KL, Ho M, Zhang X, Chen Y, Li T, Rasgon NL, Watson KT, Urban AE, Gotlib IH. Robakis TK, et al. Among authors: zhang x. Mol Psychiatry. 2022 Aug;27(8):3306-3315. doi: 10.1038/s41380-022-01592-w. Epub 2022 May 16. Mol Psychiatry. 2022. PMID: 35577912 Free PMC article.

8

Cross-platform validation of neurotransmitter release impairments in schizophrenia patient-derived NRXN1-mutant neurons.

Pak C, Danko T, Mirabella VR, Wang J, Liu Y, Vangipuram M, Grieder S, Zhang X, Ward T, Huang YA, Jin K, Dexheimer P, Bardes E, Mitelpunkt A, Ma J, McLachlan M, Moore JC, Qu P, Purmann C, Dage JL, Swanson BJ, Urban AE, Aronow BJ, Pang ZP, Levinson DF, Wernig M, Südhof TC. Pak C, et al. Among authors: zhang x. Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2025598118. doi: 10.1073/pnas.2025598118. Proc Natl Acad Sci U S A. 2021. PMID: 34035170 Free PMC article.

9

Local and global chromatin interactions are altered by large genomic deletions associated with human brain development.

Zhang X, Zhang Y, Zhu X, Purmann C, Haney MS, Ward T, Khechaduri A, Yao J, Weissman SM, Urban AE. Zhang X, et al. Among authors: zhang y. Nat Commun. 2018 Dec 17;9(1):5356. doi: 10.1038/s41467-018-07766-x. Nat Commun. 2018. PMID: 30559385 Free PMC article.

10

1q21.1 microduplication: large verbal-nonverbal performance discrepancy and ddPCR assays of HYDIN/HYDIN2 copy number.

Xavier J, Zhou B, Bilan F, Zhang X, Gilbert-Dussardier B, Viaux-Savelon S, Pattni R, Ho SS, Cohen D, Levinson DF, Urban AE, Laurent-Levinson C. Xavier J, et al. Among authors: zhang x. NPJ Genom Med. 2018 Aug 22;3:24. doi: 10.1038/s41525-018-0059-2. eCollection 2018. NPJ Genom Med. 2018. PMID: 30155272 Free PMC article.

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