Dong XP - Search Results

1

TRPML3/BK complex promotes autophagy and bacterial clearance by providing a positive feedback regulation of mTOR via PI3P.

Xu M, Zhong XZ, Huang P, Jaślan D, Wang P, Sun X, Weiden EM, El Hiani Y, Grimm C, Dong XP. Xu M, et al. Among authors: dong xp. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2215777120. doi: 10.1073/pnas.2215777120. Epub 2023 Aug 16. Proc Natl Acad Sci U S A. 2023. PMID: 37585464 Free PMC article.

2

P2X4 forms functional ATP-activated cation channels on lysosomal membranes regulated by luminal pH.

Huang P, Zou Y, Zhong XZ, Cao Q, Zhao K, Zhu MX, Murrell-Lagnado R, Dong XP. Huang P, et al. Among authors: dong xp. J Biol Chem. 2014 Jun 20;289(25):17658-67. doi: 10.1074/jbc.M114.552158. Epub 2014 May 9. J Biol Chem. 2014. PMID: 24817123 Free PMC article.

3

SLC17A9 protein functions as a lysosomal ATP transporter and regulates cell viability.

Cao Q, Zhao K, Zhong XZ, Zou Y, Yu H, Huang P, Xu TL, Dong XP. Cao Q, et al. Among authors: dong xp. J Biol Chem. 2014 Aug 15;289(33):23189-23199. doi: 10.1074/jbc.M114.567107. Epub 2014 Jun 24. J Biol Chem. 2014. PMID: 24962569 Free PMC article.

4

Lysosome electrophysiology.

Zhong XZ, Dong XP. Zhong XZ, et al. Among authors: dong xp. Methods Cell Biol. 2015;126:197-215. doi: 10.1016/bs.mcb.2014.10.022. Epub 2015 Jan 14. Methods Cell Biol. 2015. PMID: 25665447

5

BK Channels Alleviate Lysosomal Storage Diseases by Providing Positive Feedback Regulation of Lysosomal Ca2+ Release.

Cao Q, Zhong XZ, Zou Y, Zhang Z, Toro L, Dong XP. Cao Q, et al. Among authors: dong xp. Dev Cell. 2015 May 26;33(4):427-41. doi: 10.1016/j.devcel.2015.04.010. Epub 2015 May 14. Dev Cell. 2015. PMID: 25982675 Free article.

6

Calcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion.

Cao Q, Zhong XZ, Zou Y, Murrell-Lagnado R, Zhu MX, Dong XP. Cao Q, et al. Among authors: dong xp. J Cell Biol. 2015 Jun 22;209(6):879-94. doi: 10.1083/jcb.201409071. J Cell Biol. 2015. PMID: 26101220 Free PMC article.

7

Activation of lysosomal P2X4 by ATP transported into lysosomes via VNUT/SLC17A9 using V-ATPase generated voltage gradient as the driving force.

Zhong XZ, Cao Q, Sun X, Dong XP. Zhong XZ, et al. Among authors: dong xp. J Physiol. 2016 Aug 1;594(15):4253-66. doi: 10.1113/JP271893. Epub 2016 May 29. J Physiol. 2016. PMID: 27477609 Free PMC article.

8

BK channel agonist represents a potential therapeutic approach for lysosomal storage diseases.

Zhong XZ, Sun X, Cao Q, Dong G, Schiffmann R, Dong XP. Zhong XZ, et al. Among authors: dong xp, dong g. Sci Rep. 2016 Sep 27;6:33684. doi: 10.1038/srep33684. Sci Rep. 2016. PMID: 27670435 Free PMC article.

9

Methods for monitoring Ca²⁺ and ion channels in the lysosome.

Zhong XZ, Yang Y, Sun X, Dong XP. Zhong XZ, et al. Among authors: dong xp. Cell Calcium. 2017 Jun;64:20-28. doi: 10.1016/j.ceca.2016.12.001. Epub 2016 Dec 9. Cell Calcium. 2017. PMID: 27986285 Review.

10

Inhibition of Transient Receptor Potential Channel Mucolipin-1 (TRPML1) by Lysosomal Adenosine Involved in Severe Combined Immunodeficiency Diseases.

Zhong XZ, Zou Y, Sun X, Dong G, Cao Q, Pandey A, Rainey JK, Zhu X, Dong XP. Zhong XZ, et al. Among authors: dong xp, dong g. J Biol Chem. 2017 Feb 24;292(8):3445-3455. doi: 10.1074/jbc.M116.743963. Epub 2017 Jan 13. J Biol Chem. 2017. PMID: 28087698 Free PMC article.

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