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Page 1
Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins.
Nowak K, Rosenthal F, Karlberg T, Bütepage M, Thorsell AG, Dreier B, Grossmann J, Sobek J, Imhof R, Lüscher B, Schüler H, Plückthun A, Leslie Pedrioli DM, Hottiger MO. Nowak K, et al. Among authors: leslie pedrioli dm. Nat Commun. 2020 Oct 15;11(1):5199. doi: 10.1038/s41467-020-18981-w. Nat Commun. 2020. PMID: 33060572 Free PMC article.
Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death.
Liu L, Sandow JJ, Leslie Pedrioli DM, Samson AL, Silke N, Kratina T, Ambrose RL, Doerflinger M, Hu Z, Morrish E, Chau D, Kueh AJ, Fitzibbon C, Pellegrini M, Pearson JS, Hottiger MO, Webb AI, Lalaoui N, Silke J. Liu L, et al. Among authors: leslie pedrioli dm. Sci Adv. 2022 May 13;8(19):eabh2332. doi: 10.1126/sciadv.abh2332. Epub 2022 May 11. Sci Adv. 2022. PMID: 35544574 Free PMC article.
Combinatorial Treatment with PARP and MAPK Inhibitors Overcomes Phenotype Switch-Driven Drug Resistance in Advanced Melanoma.
Ferretti LP, Böhi F, Leslie Pedrioli DM, Cheng PF, Ferrari E, Baumgaertner P, Alvarado-Diaz A, Sella F, Cereghetti A, Turko P, Wright RH, De Bock K, Speiser DE, Ferrari R, Levesque MP, Hottiger MO. Ferretti LP, et al. Among authors: leslie pedrioli dm. Cancer Res. 2023 Dec 1;83(23):3974-3988. doi: 10.1158/0008-5472.CAN-23-0485. Cancer Res. 2023. PMID: 37729428
PRAMEL7 and CUL2 decrease NuRD stability to establish ground-state pluripotency.
Rupasinghe M, Bersaglieri C, Leslie Pedrioli DM, Pedrioli PG, Panatta M, Hottiger MO, Cinelli P, Santoro R. Rupasinghe M, et al. Among authors: leslie pedrioli dm. EMBO Rep. 2024 Mar;25(3):1453-1468. doi: 10.1038/s44319-024-00083-z. Epub 2024 Feb 8. EMBO Rep. 2024. PMID: 38332149 Free PMC article.
Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy.
Allen EH, Courtney DG, Atkinson SD, Moore JE, Mairs L, Poulsen ET, Schiroli D, Maurizi E, Cole C, Hickerson RP, James J, Murgatroyd H, Smith FJ, MacEwen C, Enghild JJ, Nesbit MA, Leslie Pedrioli DM, McLean WH, Moore CB. Allen EH, et al. Among authors: leslie pedrioli dm. Hum Mol Genet. 2016 Mar 15;25(6):1176-91. doi: 10.1093/hmg/ddw001. Epub 2016 Jan 11. Hum Mol Genet. 2016. PMID: 26758872 Free PMC article.
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