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Fatty acid binding protein 5 suppression attenuates obesity-induced hepatocellular carcinoma by promoting ferroptosis and intratumoral immune rewiring.
Sun J, Esplugues E, Bort A, Cardelo MP, Ruz-Maldonado I, Fernández-Tussy P, Wong C, Wang H, Ojima I, Kaczocha M, Perry R, Suárez Y, Fernández-Hernando C. Sun J, et al. Among authors: esplugues e. Nat Metab. 2024 Apr;6(4):741-763. doi: 10.1038/s42255-024-01019-6. Epub 2024 Apr 25. Nat Metab. 2024. PMID: 38664583
Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice.
Boutagy NE, Gamez-Mendez A, Fowler JW, Zhang H, Chaube BK, Esplugues E, Kuo A, Lee S, Horikami D, Zhang J, Citrin KM, Singh AK, Coon BG, Lee MY, Suarez Y, Fernandez-Hernando C, Sessa WC. Boutagy NE, et al. Among authors: esplugues e. J Clin Invest. 2024 Jan 4;134(4):e170453. doi: 10.1172/JCI170453. J Clin Invest. 2024. PMID: 38175710 Free PMC article.
SARS-CoV-2-encoded small RNAs are able to repress the host expression of SERINC5 to facilitate viral replication.
Meseguer S, Rubio MP, Lainez B, Pérez-Benavente B, Pérez-Moraga R, Romera-Giner S, García-García F, Martinez-Macias O, Cremades A, Iborra FJ, Candelas-Rivera O, Almazan F, Esplugues E. Meseguer S, et al. Among authors: esplugues e. Front Microbiol. 2023 Feb 16;14:1066493. doi: 10.3389/fmicb.2023.1066493. eCollection 2023. Front Microbiol. 2023. PMID: 36876111 Free PMC article.
The induction and function of the anti-inflammatory fate of TH17 cells.
Xu H, Agalioti T, Zhao J, Steglich B, Wahib R, Vesely MCA, Bielecki P, Bailis W, Jackson R, Perez D, Izbicki J, Licona-Limón P, Kaartinen V, Geginat J, Esplugues E, Tolosa E, Huber S, Flavell RA, Gagliani N. Xu H, et al. Among authors: esplugues e. Nat Commun. 2020 Jul 3;11(1):3334. doi: 10.1038/s41467-020-17097-5. Nat Commun. 2020. PMID: 32620760 Free PMC article.
Effector TH17 Cells Give Rise to Long-Lived TRM Cells that Are Essential for an Immediate Response against Bacterial Infection.
Amezcua Vesely MC, Pallis P, Bielecki P, Low JS, Zhao J, Harman CCD, Kroehling L, Jackson R, Bailis W, Licona-Limón P, Xu H, Iijima N, Pillai PS, Kaplan DH, Weaver CT, Kluger Y, Kowalczyk MS, Iwasaki A, Pereira JP, Esplugues E, Gagliani N, Flavell RA. Amezcua Vesely MC, et al. Among authors: esplugues e. Cell. 2019 Aug 22;178(5):1176-1188.e15. doi: 10.1016/j.cell.2019.07.032. Cell. 2019. PMID: 31442406 Free PMC article.
Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression.
Calcinotto A, Brevi A, Chesi M, Ferrarese R, Garcia Perez L, Grioni M, Kumar S, Garbitt VM, Sharik ME, Henderson KJ, Tonon G, Tomura M, Miwa Y, Esplugues E, Flavell RA, Huber S, Canducci F, Rajkumar VS, Bergsagel PL, Bellone M. Calcinotto A, et al. Among authors: esplugues e. Nat Commun. 2018 Dec 3;9(1):4832. doi: 10.1038/s41467-018-07305-8. Nat Commun. 2018. PMID: 30510245 Free PMC article.
TH17 cells express ST2 and are controlled by the alarmin IL-33 in the small intestine.
Pascual-Reguant A, Bayat Sarmadi J, Baumann C, Noster R, Cirera-Salinas D, Curato C, Pelczar P, Huber S, Zielinski CE, Löhning M, Hauser AE, Esplugues E. Pascual-Reguant A, et al. Among authors: esplugues e. Mucosal Immunol. 2017 Nov;10(6):1431-1442. doi: 10.1038/mi.2017.5. Epub 2017 Feb 15. Mucosal Immunol. 2017. PMID: 28198366 Free article.
IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo.
Brockmann L, Gagliani N, Steglich B, Giannou AD, Kempski J, Pelczar P, Geffken M, Mfarrej B, Huber F, Herkel J, Wan YY, Esplugues E, Battaglia M, Krebs CF, Flavell RA, Huber S. Brockmann L, et al. Among authors: esplugues e. J Immunol. 2017 Feb 1;198(3):1130-1141. doi: 10.4049/jimmunol.1601045. Epub 2016 Dec 21. J Immunol. 2017. PMID: 28003377 Free PMC article.
37 results