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Phosphorylation modulates clearance of alpha-synuclein inclusions in a yeast model of Parkinson's disease.
Tenreiro S, Reimão-Pinto MM, Antas P, Rino J, Wawrzycka D, Macedo D, Rosado-Ramos R, Amen T, Waiss M, Magalhães F, Gomes A, Santos CN, Kaganovich D, Outeiro TF. Tenreiro S, et al. Among authors: outeiro tf. PLoS Genet. 2014 May 8;10(5):e1004302. doi: 10.1371/journal.pgen.1004302. eCollection 2014 May. PLoS Genet. 2014. PMID: 24810576 Free PMC article.
Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation.
Lázaro DF, Rodrigues EF, Langohr R, Shahpasandzadeh H, Ribeiro T, Guerreiro P, Gerhardt E, Kröhnert K, Klucken J, Pereira MD, Popova B, Kruse N, Mollenhauer B, Rizzoli SO, Braus GH, Danzer KM, Outeiro TF. Lázaro DF, et al. Among authors: outeiro tf. PLoS Genet. 2014 Nov 13;10(11):e1004741. doi: 10.1371/journal.pgen.1004741. eCollection 2014 Nov. PLoS Genet. 2014. PMID: 25393002 Free PMC article.
The Interplay between Alpha-Synuclein Clearance and Spreading.
Lopes da Fonseca T, Villar-Piqué A, Outeiro TF. Lopes da Fonseca T, et al. Among authors: outeiro tf. Biomolecules. 2015 Apr 14;5(2):435-71. doi: 10.3390/biom5020435. Biomolecules. 2015. PMID: 25874605 Free PMC article. Review.
shRNA-Based Screen Identifies Endocytic Recycling Pathway Components That Act as Genetic Modifiers of Alpha-Synuclein Aggregation, Secretion and Toxicity.
Gonçalves SA, Macedo D, Raquel H, Simões PD, Giorgini F, Ramalho JS, Barral DC, Ferreira Moita L, Outeiro TF. Gonçalves SA, et al. Among authors: outeiro tf. PLoS Genet. 2016 Apr 28;12(4):e1005995. doi: 10.1371/journal.pgen.1005995. eCollection 2016 Apr. PLoS Genet. 2016. PMID: 27123591 Free PMC article.
349 results