Sant'Anna R - Search Results

1

The alpha-synuclein oligomers activate nuclear factor of activated T-cell (NFAT) modulating synaptic homeostasis and apoptosis.

Sant'Anna R, Robbs BK, de Freitas JA, Dos Santos PP, König A, Outeiro TF, Foguel D. Sant'Anna R, et al. Mol Med. 2023 Aug 18;29(1):111. doi: 10.1186/s10020-023-00704-8. Mol Med. 2023. PMID: 37596531 Free PMC article.

2

Extracellular alpha-synuclein: Sensors, receptors, and responses.

Domingues R, Sant'Anna R, da Fonseca ACC, Robbs BK, Foguel D, Outeiro TF. Domingues R, et al. Neurobiol Dis. 2022 Jun 15;168:105696. doi: 10.1016/j.nbd.2022.105696. Epub 2022 Mar 20. Neurobiol Dis. 2022. PMID: 35321855 Free article. Review.

3

Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity.

Villar-Piqué A, Lopes da Fonseca T, Sant'Anna R, Szegö ÉM, Fonseca-Ornelas L, Pinho R, Carija A, Gerhardt E, Masaracchia C, Abad Gonzalez E, Rossetti G, Carloni P, Fernández CO, Foguel D, Milosevic I, Zweckstetter M, Ventura S, Outeiro TF. Villar-Piqué A, et al. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):E6506-E6515. doi: 10.1073/pnas.1606791113. Epub 2016 Oct 5. Proc Natl Acad Sci U S A. 2016. PMID: 27708160 Free PMC article.

4

Peptides derived from gp43, the most antigenic protein from Paracoccidioides brasiliensis, form amyloid fibrils in vitro: implications for vaccine development.

Cardim-Pires TR, Sant'Anna R, Foguel D. Cardim-Pires TR, et al. Sci Rep. 2021 Dec 6;11(1):23440. doi: 10.1038/s41598-021-02898-5. Sci Rep. 2021. PMID: 34873233 Free PMC article.

5

Inhibition of human transthyretin aggregation by non-steroidal anti-inflammatory compounds: a structural and thermodynamic analysis.

Sant'anna RO, Braga CA, Polikarpov I, Ventura S, Lima LM, Foguel D. Sant'anna RO, et al. Int J Mol Sci. 2013 Mar 6;14(3):5284-311. doi: 10.3390/ijms14035284. Int J Mol Sci. 2013. PMID: 23466880 Free PMC article.

6

Amyloid properties of the leader peptide of variant B cystatin C: implications for Alzheimer and macular degeneration.

Sant'Anna R, Navarro S, Ventura S, Paraoan L, Foguel D. Sant'Anna R, et al. FEBS Lett. 2016 Mar;590(5):644-54. doi: 10.1002/1873-3468.12093. Epub 2016 Feb 26. FEBS Lett. 2016. PMID: 26865059 Free article.

7

Connection between MHC class II binding and aggregation propensity: The antigenic peptide 10 of Paracoccidioides brasiliensis as a benchmark study.

Ochoa R, Cardim-Pires TR, Sant'Anna R, Cossio P, Foguel D. Ochoa R, et al. Comput Struct Biotechnol J. 2023 Feb 18;21:1746-1758. doi: 10.1016/j.csbj.2023.02.031. eCollection 2023. Comput Struct Biotechnol J. 2023. PMID: 36890879 Free PMC article.

8

The importance of a gatekeeper residue on the aggregation of transthyretin: implications for transthyretin-related amyloidoses.

Sant'Anna R, Braga C, Varejão N, Pimenta KM, Graña-Montes R, Alves A, Cortines J, Cordeiro Y, Ventura S, Foguel D. Sant'Anna R, et al. J Biol Chem. 2014 Oct 10;289(41):28324-37. doi: 10.1074/jbc.M114.563981. Epub 2014 Aug 1. J Biol Chem. 2014. PMID: 25086037 Free PMC article.

9

Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.

Sant'Anna R, Almeida MR, Varejāo N, Gallego P, Esperante S, Ferreira P, Pereira-Henriques A, Palhano FL, de Carvalho M, Foguel D, Reverter D, Saraiva MJ, Ventura S. Sant'Anna R, et al. Sci Rep. 2017 Mar 24;7:44709. doi: 10.1038/srep44709. Sci Rep. 2017. PMID: 28338000 Free PMC article.

10

Structure-based analysis of A19D, a variant of transthyretin involved in familial amyloid cardiomyopathy.

Ferreira P, Sant'Anna R, Varejão N, Lima C, Novis S, Barbosa RV, Caldeira CM, Rumjanek FD, Ventura S, Cruz MW, Foguel D. Ferreira P, et al. PLoS One. 2013 Dec 17;8(12):e82484. doi: 10.1371/journal.pone.0082484. eCollection 2013. PLoS One. 2013. PMID: 24358189 Free PMC article.

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