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527 results

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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
House IG, Derrick EB, Sek K, Chen AXY, Li J, Lai J, Todd KL, Munoz I, Michie J, Chan CW, Huang YK, Chan JD, Petley EV, Tong J, Nguyen D, Engel S, Savas P, Hogg SJ, Vervoort SJ, Kearney CJ, Burr ML, Lam EYN, Gilan O, Bedoui S, Johnstone RW, Dawson MA, Loi S, Darcy PK, Beavis PA. House IG, et al. Among authors: loi s. Cell Rep. 2023 Aug 29;42(8):113014. doi: 10.1016/j.celrep.2023.113014. Epub 2023 Aug 21. Cell Rep. 2023. PMID: 37605534 Free article.
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
House IG, Derrick EB, Sek K, Chen AXY, Li J, Lai J, Todd KL, Munoz I, Michie J, Chan CW, Huang YK, Chan JD, Petley EV, Tong J, Nguyen D, Engel S, Savas P, Hogg SJ, Vervoort SJ, Kearney CJ, Burr ML, Lam EYN, Gilan O, Bedoui S, Johnstone RW, Dawson MA, Loi S, Darcy PK, Beavis PA. House IG, et al. Among authors: loi s. Cell Rep. 2024 Feb 27;43(2):113793. doi: 10.1016/j.celrep.2024.113793. Epub 2024 Feb 5. Cell Rep. 2024. PMID: 38324452 Free article. No abstract available.
The next big questions in cancer research.
Loi S, Settleman J, Joyce JA, Pramesh CS, Bernards R, Fan J, Merchant JL, Moslehi J, Sellers WR. Loi S, et al. Cell. 2023 Apr 13;186(8):1523-1527. doi: 10.1016/j.cell.2023.01.037. Cell. 2023. PMID: 37059060 Free article.
Strong diagnostic performance of plasma ptau217 for CSF biomarker-defined young-onset Alzheimer disease in a diagnostically heterogeneous clinical cohort.
Eratne D, Li QX, Lewis C, Dang C, Kang MJY, Grewal J, Loi S, Walterfang M, Evans AH, Malpas CB, Pedrini S, Martins R, Chatterjee P, Zetterberg H, Blennow K, Berkovic SF, Santillo AF, Collins S, Masters CL, Velakoulis D; MiND Study Group. Eratne D, et al. Among authors: loi s. J Neurol. 2024 Dec 12;272(1):25. doi: 10.1007/s00415-024-12732-3. J Neurol. 2024. PMID: 39666133
Identification of HER2-positive breast cancer molecular subtypes with potential clinical implications in the ALTTO clinical trial.
Rediti M, Venet D, Joaquin Garcia A, Maetens M, Vincent D, Majjaj S, El-Abed S, Di Cosimo S, Ueno T, Izquierdo M, Piccart M, Pusztai L, Loi S, Salgado R, Viale G, Rothé F, Sotiriou C. Rediti M, et al. Among authors: loi s. Nat Commun. 2024 Nov 29;15(1):10402. doi: 10.1038/s41467-024-54621-3. Nat Commun. 2024. PMID: 39613746 Free PMC article.
Gaps in biomedical research in frontotemporal dementia: A call for diversity and disparities focused research.
Nuytemans K, Franzen S, Broce IJ, Caramelli P, Ellajosyula R, Finger E, Gupta V, Gupta V, Illán-Gala I, Loi SM, Morhardt D, Pijnenburg Y, Rascovsky K, Williams MM, Yokoyama JS, Acosta-Uribe J, Akinyemi R, Alladi S, Ayele BA, Ayhan Y, Bourdage R, Castro-Suarez S, de Souza LC, Dacks P, de Boer SCM, de Leon J, Dodge S, Grasso S, Ghoshal N, Kamath V, Kumfor F, Matias-Guiu JA, Narme P, Nielsen TR, Okhuevbie D, Piña-Escudero S, Ruiz-Garcia R, Ryan B, Scarioni M, Slachevsky A, Suarez-Gonzalez A, Tee BL, Tsoy E, Ulugut H, Onyike CU, Babulal GM; ISTAART Frontotemporal Dementia and Related Disorders PIA, ISTAART Diversity and Disparities PIA. Nuytemans K, et al. Among authors: loi sm. Alzheimers Dement. 2024 Dec;20(12):9014-9036. doi: 10.1002/alz.14312. Epub 2024 Nov 13. Alzheimers Dement. 2024. PMID: 39535468 Free PMC article. Review.
Inavolisib-Based Therapy in PIK3CA-Mutated Advanced Breast Cancer.
Turner NC, Im SA, Saura C, Juric D, Loibl S, Kalinsky K, Schmid P, Loi S, Sunpaweravong P, Musolino A, Li H, Zhang Q, Nowecki Z, Leung R, Thanopoulou E, Shankar N, Lei G, Stout TJ, Hutchinson KE, Schutzman JL, Song C, Jhaveri KL. Turner NC, et al. Among authors: loi s. N Engl J Med. 2024 Oct 31;391(17):1584-1596. doi: 10.1056/NEJMoa2404625. N Engl J Med. 2024. PMID: 39476340 Clinical Trial.
A phase III trial of adjuvant ribociclib plus endocrine therapy versus endocrine therapy alone in patients with HR-positive/HER2-negative early breast cancer: final invasive disease-free survival results from the NATALEE trial.
Hortobagyi GN, Lacko A, Sohn J, Cruz F, Ruiz Borrego M, Manikhas A, Hee Park Y, Stroyakovskiy D, Yardley DA, Huang CS, Fasching PA, Crown J, Bardia A, Chia S, Im SA, Martin M, Loi S, Xu B, Hurvitz S, Barrios C, Untch M, Moroose R, Visco F, Parnizari F, Zarate JP, Li Z, Waters S, Chakravartty A, Slamon D. Hortobagyi GN, et al. Among authors: loi s. Ann Oncol. 2024 Oct 21:S0923-7534(24)04064-X. doi: 10.1016/j.annonc.2024.10.015. Online ahead of print. Ann Oncol. 2024. PMID: 39442617 Free article.
527 results