Zhang H - Search Results

1

Inhibitors Targeting the F-BOX Proteins.

Naseem Y, Zhang C, Zhou X, Dong J, Xie J, Zhang H, Agboyibor C, Bi Y, Liu H. Naseem Y, et al. Among authors: zhang c, zhang h. Cell Biochem Biophys. 2023 Dec;81(4):577-597. doi: 10.1007/s12013-023-01160-1. Epub 2023 Aug 25. Cell Biochem Biophys. 2023. PMID: 37624574 Review.

2

Optimization of 4,6-Disubstituted Pyrido[3,2-d]pyrimidines as Dual MNK/PIM Inhibitors to Inhibit Leukemia Cell Growth.

Han Y, Zhang H, Wang S, Li B, Xing K, Shi Y, Cao H, Zhang J, Tong T, Zang J, Guan L, Gao X, Wang Y, Liu D, Huang M, Jing Y, Zhao L. Han Y, et al. Among authors: zhang j, zhang h. J Med Chem. 2021 Sep 23;64(18):13719-13735. doi: 10.1021/acs.jmedchem.1c01084. Epub 2021 Sep 13. J Med Chem. 2021. PMID: 34515481

3

Design, synthesis and biological evaluation of novel hybrids targeting mTOR and HDACs for potential treatment of hepatocellular carcinoma.

Zhai S, Zhang H, Chen R, Wu J, Ai D, Tao S, Cai Y, Zhang JQ, Wang L. Zhai S, et al. Among authors: zhang jq, zhang h. Eur J Med Chem. 2021 Dec 5;225:113824. doi: 10.1016/j.ejmech.2021.113824. Epub 2021 Sep 3. Eur J Med Chem. 2021. PMID: 34509167

4

Design, synthesis and biological evaluation of 4-(indolin-1-yl)-6-substituted-pyrido[3,2-d]pyrimidine derivatives as Mnk1/2 inhibitors.

Xing K, Zhang H, Wang S, Li J, Mu Z, Zhang L, Zuo S, Wang Y, Li S, Wu B, Jing Y, Wen J, Liu D, Huang M, Zhao L. Xing K, et al. Among authors: zhang l, zhang h. Eur J Med Chem. 2024 Jun 5;272:116499. doi: 10.1016/j.ejmech.2024.116499. Epub 2024 May 14. Eur J Med Chem. 2024. PMID: 38759457

5

Targeting the RT loop of Src SH3 in Platelets Prevents Thrombosis without Compromising Hemostasis.

Mao J, Zhu K, Long Z, Zhang H, Xiao B, Xi W, Wang Y, Huang J, Liu J, Shi X, Jiang H, Lu T, Wen Y, Zhang N, Meng Q, Zhou H, Ruan Z, Wang J, Luo C, Xi X. Mao J, et al. Among authors: zhang n, zhang h. Adv Sci (Weinh). 2022 Mar;9(7):e2103228. doi: 10.1002/advs.202103228. Epub 2022 Jan 12. Adv Sci (Weinh). 2022. PMID: 35023301 Free PMC article.

6

Discovery of a Covalent Inhibitor Selectively Targeting the Autophosphorylation Site of c-Src Kinase.

Zhang H, Xu D, Huang H, Jiang H, Hu L, Liu L, Sun G, Gao J, Li Y, Xia C, Chen S, Zhou H, Kong X, Wang M, Luo C. Zhang H, et al. ACS Chem Biol. 2024 Apr 19;19(4):999-1010. doi: 10.1021/acschembio.4c00048. Epub 2024 Mar 21. ACS Chem Biol. 2024. PMID: 38513196

7

Synthesis and biological evaluation of new series of benzamide derivatives containing urea moiety as sEH inhibitors.

Tian Y, Li S, Yang P, Su X, Liu J, Lv X, Dong K, Yang T, Duan M, Hu G, Yue H, Sun Y, Sun Y, Zhang H, Du Z, Miao Z, Tong M, Hou Y, Gao Z, Zhao Y. Tian Y, et al. Among authors: zhang h. Bioorg Med Chem Lett. 2022 Aug 15;70:128805. doi: 10.1016/j.bmcl.2022.128805. Epub 2022 May 19. Bioorg Med Chem Lett. 2022. PMID: 35598794

8

Discovery of benzamide derivatives containing urea moiety as soluble epoxide hydrolase inhibitors.

Tian Y, Li S, Dong K, Su X, Fu S, Lv X, Duan M, Yang T, Han Y, Hu G, Liu J, Sun Y, Yue H, Sun Y, Zhang H, Du Z, Miao Z, Tong M, Liu Y, Qin M, Gong P, Hou Y, Gao Z, Zhao Y. Tian Y, et al. Among authors: zhang h. Bioorg Chem. 2022 Oct;127:105898. doi: 10.1016/j.bioorg.2022.105898. Epub 2022 May 24. Bioorg Chem. 2022. PMID: 35792317

9

Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family.

Zhang H, He J, Hu G, Zhu F, Jiang H, Gao J, Zhou H, Lin H, Wang Y, Chen K, Meng F, Hao M, Zhao K, Luo C, Liang Z. Zhang H, et al. J Med Chem. 2021 Oct 28;64(20):15111-15125. doi: 10.1021/acs.jmedchem.1c01076. Epub 2021 Oct 20. J Med Chem. 2021. PMID: 34668699

10

Ligand- and structure-based identification of novel CDK9 inhibitors for the potential treatment of leukemia.

Zhang H, Huang J, Chen R, Cai H, Chen Y, He S, Xu J, Zhang J, Wang L. Zhang H, et al. Among authors: zhang j. Bioorg Med Chem. 2022 Oct 15;72:116994. doi: 10.1016/j.bmc.2022.116994. Epub 2022 Sep 5. Bioorg Med Chem. 2022. PMID: 36087428

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