Harborne S - Search Results

1

Key aspects of modern GPCR drug discovery.

Addis P, Bali U, Baron F, Campbell A, Harborne S, Jagger L, Milne G, Pearce M, Rosethorne EM, Satchell R, Swift D, Young B, Unitt JF. Addis P, et al. Among authors: harborne s. SLAS Discov. 2024 Jan;29(1):1-22. doi: 10.1016/j.slasd.2023.08.007. Epub 2023 Aug 23. SLAS Discov. 2024. PMID: 37625784 Free article. Review.

2

Rapid Assessment of Membrane Protein Quality by Fluorescent Size Exclusion Chromatography.

Rejnowicz E, Wright J, Veldman-Jones M, Harborne S. Rejnowicz E, et al. Among authors: harborne s. J Vis Exp. 2023 Jan 6;(191). doi: 10.3791/64322. J Vis Exp. 2023. PMID: 36688542

3

Novel variants provide differential stabilisation of human equilibrative nucleoside transporter 1 states.

Boakes JC, Harborne SPD, Ngo JTS, Pliotas C, Goldman A. Boakes JC, et al. Among authors: harborne spd. Front Mol Biosci. 2022 Nov 8;9:970391. doi: 10.3389/fmolb.2022.970391. eCollection 2022. Front Mol Biosci. 2022. PMID: 36425655 Free PMC article.

4

Thermostability Assays: a Generic and Versatile Tool for Studying the Functional and Structural Properties of Membrane Proteins in Detergents.

Harborne SPD, King MS, Kunji ERS. Harborne SPD, et al. Methods Mol Biol. 2020;2168:105-121. doi: 10.1007/978-1-0716-0724-4_5. Methods Mol Biol. 2020. PMID: 33582989

5

IMPROvER: the Integral Membrane Protein Stability Selector.

Harborne SPD, Strauss J, Boakes JC, Wright DL, Henderson JG, Boivineau J, Jaakola VP, Goldman A. Harborne SPD, et al. Sci Rep. 2020 Sep 16;10(1):15165. doi: 10.1038/s41598-020-71744-x. Sci Rep. 2020. PMID: 32938971 Free PMC article.

6

Calcium-regulated mitochondrial ATP-Mg/P_i carriers evolved from a fusion of an EF-hand regulatory domain with a mitochondrial ADP/ATP carrier-like domain.

Harborne SPD, Kunji ERS. Harborne SPD, et al. IUBMB Life. 2018 Dec;70(12):1222-1232. doi: 10.1002/iub.1931. Epub 2018 Oct 3. IUBMB Life. 2018. PMID: 30281880 Free PMC article. Review.

7

Defining Dynamics of Membrane-Bound Pyrophosphatases by Experimental and Computational Single-Molecule FRET.

Harborne SPD, Strauss J, Turku A, Watson MA, Tuma R, Harris SA, Goldman A. Harborne SPD, et al. Methods Enzymol. 2018;607:93-130. doi: 10.1016/bs.mie.2018.04.017. Methods Enzymol. 2018. PMID: 30149870

8

A Simple Strategy to Determine the Dependence of Membrane-Bound Pyrophosphatases on K⁺ as a Cofactor.

Strauss J, Wilkinson C, Vidilaseris K, Harborne SPD, Goldman A. Strauss J, et al. Among authors: harborne spd. Methods Enzymol. 2018;607:131-156. doi: 10.1016/bs.mie.2018.04.018. Epub 2018 Jun 1. Methods Enzymol. 2018. PMID: 30149856

9

Pacing across the membrane: the novel PACE family of efflux pumps is widespread in Gram-negative pathogens.

Hassan KA, Liu Q, Elbourne LDH, Ahmad I, Sharples D, Naidu V, Chan CL, Li L, Harborne SPD, Pokhrel A, Postis VLG, Goldman A, Henderson PJF, Paulsen IT. Hassan KA, et al. Among authors: harborne spd. Res Microbiol. 2018 Sep-Oct;169(7-8):450-454. doi: 10.1016/j.resmic.2018.01.001. Epub 2018 Feb 2. Res Microbiol. 2018. PMID: 29409983 Free PMC article. Review.

10

Calcium regulation of the human mitochondrial ATP-Mg/Pi carrier SLC25A24 uses a locking pin mechanism.

Harborne SP, King MS, Crichton PG, Kunji ER. Harborne SP, et al. Sci Rep. 2017 Mar 28;7:45383. doi: 10.1038/srep45383. Sci Rep. 2017. PMID: 28350015 Free PMC article.

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