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STAT5 confers lactogenic properties in breast tumorigenesis and restricts metastatic potential.
Lin M, Ku AT, Dong J, Yue F, Jiang W, Ibrahim AA, Peng F, Creighton CJ, Nagi C, Gutierrez C, Rosen JM, Zhang XH, Hilsenbeck SG, Chen X, Du YN, Huang S, Shi A, Fan Z, Li Y. Lin M, et al. Among authors: huang s. Oncogene. 2022 Nov;41(48):5214-5222. doi: 10.1038/s41388-022-02500-w. Epub 2022 Oct 19. Oncogene. 2022. PMID: 36261627 Free PMC article.
SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells.
Zhang L, Hsu JI, Braekeleer ED, Chen CW, Patel TD, Martell AG, Guzman AG, Wohlan K, Waldvogel SM, Urya H, Tovy A, Callen E, Murdaugh R, Richard R, Jansen S, Vissers L, de Vries BBA, Nussenzweig A, Huang S, Coarfa C, Anastas JN, Takahashi K, Vassiliou G, Goodell MA. Zhang L, et al. Among authors: huang s. bioRxiv [Preprint]. 2024 Jan 17:2023.08.31.555634. doi: 10.1101/2023.08.31.555634. bioRxiv. 2024. Update in: Elife. 2024 Jun 18;12:RP91611. doi: 10.7554/eLife.91611 PMID: 37693622 Free PMC article. Updated. Preprint.
Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation.
Welte T, Kim IS, Tian L, Gao X, Wang H, Li J, Holdman XB, Herschkowitz JI, Pond A, Xie G, Kurley S, Nguyen T, Liao L, Dobrolecki LE, Pang L, Mo Q, Edwards DP, Huang S, Xin L, Xu J, Li Y, Lewis MT, Wang T, Westbrook TF, Rosen JM, Zhang XH. Welte T, et al. Among authors: huang s. Nat Cell Biol. 2016 Jun;18(6):632-44. doi: 10.1038/ncb3355. Epub 2016 May 16. Nat Cell Biol. 2016. PMID: 27183469 Free PMC article.
Consequences of early postnatal lipopolysaccharide exposure on developing lungs in mice.
Shrestha AK, Bettini ML, Menon RT, Gopal VYN, Huang S, Edwards DP, Pammi M, Barrios R, Shivanna B. Shrestha AK, et al. Among authors: huang s. Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L229-L244. doi: 10.1152/ajplung.00560.2017. Epub 2018 Oct 11. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 30307313 Free PMC article.
The REGγ proteasome regulates hepatic lipid metabolism through inhibition of autophagy.
Dong S, Jia C, Zhang S, Fan G, Li Y, Shan P, Sun L, Xiao W, Li L, Zheng Y, Liu J, Wei H, Hu C, Zhang W, Chin YE, Zhai Q, Li Q, Liu J, Jia F, Mo Q, Edwards DP, Huang S, Chan L, O'Malley BW, Li X, Wang C. Dong S, et al. Among authors: huang s. Cell Metab. 2013 Sep 3;18(3):380-91. doi: 10.1016/j.cmet.2013.08.012. Cell Metab. 2013. PMID: 24011073 Free PMC article.
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