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c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate.
Edmunds LR, Sharma L, Kang A, Lu J, Vockley J, Basu S, Uppala R, Goetzman ES, Beck ME, Scott D, Prochownik EV. Edmunds LR, et al. Among authors: prochownik ev. J Biol Chem. 2014 Sep 5;289(36):25382-92. doi: 10.1074/jbc.M114.580662. Epub 2014 Jul 22. J Biol Chem. 2014. PMID: 25053415 Free PMC article.
Complex I assembly function and fatty acid oxidation enzyme activity of ACAD9 both contribute to disease severity in ACAD9 deficiency.
Schiff M, Haberberger B, Xia C, Mohsen AW, Goetzman ES, Wang Y, Uppala R, Zhang Y, Karunanidhi A, Prabhu D, Alharbi H, Prochownik EV, Haack T, Häberle J, Munnich A, Rötig A, Taylor RW, Nicholls RD, Kim JJ, Prokisch H, Vockley J. Schiff M, et al. Among authors: prochownik ev. Hum Mol Genet. 2015 Jun 1;24(11):3238-47. doi: 10.1093/hmg/ddv074. Epub 2015 Feb 26. Hum Mol Genet. 2015. PMID: 25721401 Free PMC article.
c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate.
Edmunds LR, Sharma L, Kang A, Lu J, Vockley J, Basu S, Uppala R, Goetzman ES, Beck ME, Scott D, Prochownik EV. Edmunds LR, et al. Among authors: prochownik ev. J Biol Chem. 2015 Aug 14;290(33):20100. doi: 10.1074/jbc.A114.580662. J Biol Chem. 2015. PMID: 26276854 Free PMC article. No abstract available.
Abnormal lipid processing but normal long-term repopulation potential of myc-/- hepatocytes.
Edmunds LR, Otero PA, Sharma L, D'Souza S, Dolezal JM, David S, Lu J, Lamm L, Basantani M, Zhang P, Sipula IJ, Li L, Zeng X, Ding Y, Ding F, Beck ME, Vockley J, Monga SP, Kershaw EE, O'Doherty RM, Kratz LE, Yates NA, Goetzman EP, Scott D, Duncan AW, Prochownik EV. Edmunds LR, et al. Among authors: prochownik ev. Oncotarget. 2016 May 24;7(21):30379-95. doi: 10.18632/oncotarget.8856. Oncotarget. 2016. PMID: 27105497 Free PMC article.
Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma.
Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Beer-Stolz D, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV. Wang H, et al. Among authors: prochownik ev. J Biol Chem. 2016 Dec 16;291(51):26241-26251. doi: 10.1074/jbc.M116.754218. Epub 2016 Oct 13. J Biol Chem. 2016. PMID: 27738108 Free PMC article.
Sequential adaptive changes in a c-Myc-driven model of hepatocellular carcinoma.
Dolezal JM, Wang H, Kulkarni S, Jackson L, Lu J, Ranganathan S, Goetzman ES, Bharathi SS, Beezhold K, Byersdorfer CA, Prochownik EV. Dolezal JM, et al. Among authors: prochownik ev. J Biol Chem. 2017 Jun 16;292(24):10068-10086. doi: 10.1074/jbc.M117.782052. Epub 2017 Apr 21. J Biol Chem. 2017. PMID: 28432125 Free PMC article.
Genetic Dissociation of Glycolysis and the TCA Cycle Affects Neither Normal nor Neoplastic Proliferation.
Jackson LE, Kulkarni S, Wang H, Lu J, Dolezal JM, Bharathi SS, Ranganathan S, Patel MS, Deshpande R, Alencastro F, Wendell SG, Goetzman ES, Duncan AW, Prochownik EV. Jackson LE, et al. Among authors: prochownik ev. Cancer Res. 2017 Nov 1;77(21):5795-5807. doi: 10.1158/0008-5472.CAN-17-1325. Epub 2017 Sep 7. Cancer Res. 2017. PMID: 28883002 Free PMC article.
175 results