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Small-molecule MMRi36 induces apoptosis in p53-mutant lymphomas by targeting MDM2/MDM4/XIAP for degradation.
Front Oncol. 2024 Dec 23;14:1462231. doi: 10.3389/fonc.2024.1462231. eCollection 2024.
Front Oncol. 2024.
PMID: 39763603
Free PMC article.
Population Pharmacokinetics and Pharmacodynamics of Carfilzomib in Combination with Rituximab, Ifosfamide, Carboplatin, and Etoposide in Adult Patients with Relapsed/Refractory Diffuse Large B Cell Lymphoma.
Lin LH, Ghasemi M, Burke SM, Mavis CK, Nichols JR, Torka P, Mager DE, Hernandez-Ilizaliturri FJ, Goey AKL.
Lin LH, et al. Among authors: mavis ck.
Target Oncol. 2023 Sep;18(5):685-695. doi: 10.1007/s11523-023-00992-4. Epub 2023 Aug 26.
Target Oncol. 2023.
PMID: 37632592
Free PMC article.
Clinical Trial.
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Small molecule MMRi62 targets MDM4 for degradation and induces leukemic cell apoptosis regardless of p53 status.
Lama R, Xu C, Galster SL, Querol-García J, Portwood S, Mavis CK, Ruiz FM, Martin D, Wu J, Giorgi MC, Bargonetti J, Wang ES, Hernandez-Ilizaliturri FJ, Koudelka GB, Chemler SR, Muñoz IG, Wang X.
Lama R, et al. Among authors: mavis ck.
Front Oncol. 2022 Aug 5;12:933446. doi: 10.3389/fonc.2022.933446. eCollection 2022.
Front Oncol. 2022.
PMID: 35992795
Free PMC article.
Item in Clipboard
Expression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumors.
Mavis CK, Morey Kinney SR, Foster BA, Karpf AR.
Mavis CK, et al.
Prostate. 2009 Sep 1;69(12):1312-24. doi: 10.1002/pros.20976.
Prostate. 2009.
PMID: 19444856
Free PMC article.
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