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Secretome from iPSC-derived MSCs exerts proangiogenic and immunosuppressive effects to alleviate radiation-induced vascular endothelial cell damage.
Gupta K, Perkerson RB 3rd, Parsons TM, Angom R, Amerna D, Burgess JD, Ren Y, McLean PJ, Mukhopadhyay D, Vibhute P, Wszolek ZK, Zubair AC, Quiñones-Hinojosa A, Kanekiyo T. Gupta K, et al. Among authors: amerna d. Stem Cell Res Ther. 2024 Jul 29;15(1):230. doi: 10.1186/s13287-024-03847-5. Stem Cell Res Ther. 2024. PMID: 39075600 Free PMC article.
Honokiol decreases alpha-synuclein mRNA levels and reveals novel targets for modulating alpha-synuclein expression.
Fagen SJ, Burgess JD, Lim MJ, Amerna D, Kaya ZB, Faroqi AH, Perisetla P, DeMeo NN, Stojkovska I, Quiriconi DJ, Mazzulli JR, Delenclos M, Boschen SL, McLean PJ. Fagen SJ, et al. Among authors: amerna d. Front Aging Neurosci. 2023 Aug 10;15:1179086. doi: 10.3389/fnagi.2023.1179086. eCollection 2023. Front Aging Neurosci. 2023. PMID: 37637959 Free PMC article.
A Mutant Methionyl-tRNA Synthetase-Based toolkit to assess induced-Mesenchymal Stromal Cell secretome in mixed-culture disease models.
Burgess JD, Amerna D, Norton ES, Parsons TM, Perkerson RB 3rd, Faroqi AH, Wszolek ZK, Cazares HG, Kanekiyo T, Delenclos M, McLean PJ. Burgess JD, et al. Among authors: amerna d. Res Sq [Preprint]. 2023 May 3:rs.3.rs-2838195. doi: 10.21203/rs.3.rs-2838195/v1. Res Sq. 2023. Update in: Stem Cell Res Ther. 2023 Oct 5;14(1):289. doi: 10.1186/s13287-023-03515-0 PMID: 37205579 Free PMC article. Updated. Preprint.
APOE4 exacerbates α-synuclein seeding activity and contributes to neurotoxicity in Alzheimer's disease with Lewy body pathology.
Jin Y, Li F, Sonoustoun B, Kondru NC, Martens YA, Qiao W, Heckman MG, Ikezu TC, Li Z, Burgess JD, Amerna D, O'Leary J, DeTure MA, Zhao J, McLean PJ, Dickson DW, Ross OA, Bu G, Zhao N. Jin Y, et al. Among authors: amerna d. Acta Neuropathol. 2022 Jun;143(6):641-662. doi: 10.1007/s00401-022-02421-8. Epub 2022 Apr 26. Acta Neuropathol. 2022. PMID: 35471463 Free PMC article.