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Inhibition of focal adhesion kinase enhances antitumor response of radiation therapy in pancreatic cancer through CD8+ T cells.
Osipov A, Blair AB, Liberto J, Wang J, Li K, Herbst B, Xu Y, Li S, Niu N, Rashid R, Ding D, Liu Y, Wang Z, Wolfgang CL, Burkhart RA, Laheru D, Zheng L. Osipov A, et al. Among authors: wang j, wang z. Cancer Biol Med. 2021 Feb 15;18(1):206-214. doi: 10.20892/j.issn.2095-3941.2020.0273. Cancer Biol Med. 2021. PMID: 33628595 Free PMC article.
CCR2/CCR5 inhibitor permits the radiation-induced effector T cell infiltration in pancreatic adenocarcinoma.
Wang J, Saung MT, Li K, Fu J, Fujiwara K, Niu N, Muth S, Wang J, Xu Y, Rozich N, Zlomke H, Chen S, Espinoza B, Henderson M, Funes V, Herbst B, Ding D, Twyman-Saint Victor C, Zhao Q, Narang A, He J, Zheng L. Wang J, et al. J Exp Med. 2022 May 2;219(5):e20211631. doi: 10.1084/jem.20211631. Epub 2022 Apr 11. J Exp Med. 2022. PMID: 35404390 Free PMC article.
Anti-IL-8 antibody activates myeloid cells and potentiates the anti-tumor activity of anti-PD-1 antibody in the humanized pancreatic cancer murine model.
Li P, Rozich N, Wang J, Wang J, Xu Y, Herbst B, Yu R, Muth S, Niu N, Li K, Funes V, Gai J, Osipov A, Edil BH, Wolfgang CL, Lei M, Liang T, Zheng L. Li P, et al. Among authors: wang j. Cancer Lett. 2022 Jul 28;539:215722. doi: 10.1016/j.canlet.2022.215722. Epub 2022 May 7. Cancer Lett. 2022. PMID: 35533951 Free PMC article.
Dual Stromal Targeting Sensitizes Pancreatic Adenocarcinoma for Anti-Programmed Cell Death Protein 1 Therapy.
Blair AB, Wang J, Davelaar J, Baker A, Li K, Niu N, Wang J, Shao Y, Funes V, Li P, Pachter JA, Maneval DC, Dezem F, Plummer J, Chan KS, Gong J, Hendifar AE, Pandol SJ, Burkhart R, Zhang Y, Zheng L, Osipov A. Blair AB, et al. Among authors: wang j. Gastroenterology. 2022 Nov;163(5):1267-1280.e7. doi: 10.1053/j.gastro.2022.06.027. Epub 2022 Jun 17. Gastroenterology. 2022. PMID: 35718227 Free PMC article.
CLDN18.2 BiTE Engages Effector and Regulatory T Cells for Antitumor Immune Response in Preclinical Models of Pancreatic Cancer.
Xu Y, Fu J, Henderson M, Lee F, Jurcak N, Henn A, Wahl J, Shao Y, Wang J, Lyman M, Funes V, Espinoza B, Zhang R, Washington I, Chen SY, Zlomke H, Wang J, Niu N, Li P, Meng F, Burns W, Friedrich M, Stienen S, Bailis JM, Zheng L. Xu Y, et al. Among authors: wang j. Gastroenterology. 2023 Nov;165(5):1219-1232. doi: 10.1053/j.gastro.2023.06.037. Epub 2023 Jul 26. Gastroenterology. 2023. PMID: 37507075 Free PMC article.
Overcome the challenge for intratumoral injection of STING agonist for pancreatic cancer by systemic administration.
Li K, Wang J, Zhang R, Zhou J, Espinoza B, Niu N, Wang J, Jurcak N, Rozich N, Osipov A, Henderson M, Funes V, Lyman M, Blair AB, Herbst B, He M, Yuan J, Trafton D, Yuan C, Wichroski M, Liu X, Fu J, Zheng L. Li K, et al. Among authors: wang j. J Hematol Oncol. 2024 Aug 7;17(1):62. doi: 10.1186/s13045-024-01576-z. J Hematol Oncol. 2024. PMID: 39113096 Free PMC article.
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