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STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade.
Fu J, Kanne DB, Leong M, Glickman LH, McWhirter SM, Lemmens E, Mechette K, Leong JJ, Lauer P, Liu W, Sivick KE, Zeng Q, Soares KC, Zheng L, Portnoy DA, Woodward JJ, Pardoll DM, Dubensky TW Jr, Kim Y. Fu J, et al. Among authors: zheng l. Sci Transl Med. 2015 Apr 15;7(283):283ra52. doi: 10.1126/scitranslmed.aaa4306. Sci Transl Med. 2015. PMID: 25877890 Free PMC article.
Cancer-Associated Fibroblasts in Pancreatic Cancer Are Reprogrammed by Tumor-Induced Alterations in Genomic DNA Methylation.
Xiao Q, Zhou D, Rucki AA, Williams J, Zhou J, Mo G, Murphy A, Fujiwara K, Kleponis J, Salman B, Wolfgang CL, Anders RA, Zheng S, Jaffee EM, Zheng L. Xiao Q, et al. Among authors: zheng s, zheng l. Cancer Res. 2016 Sep 15;76(18):5395-404. doi: 10.1158/0008-5472.CAN-15-3264. Epub 2016 Aug 5. Cancer Res. 2016. PMID: 27496707 Free PMC article.
DNA methylation in the tumor microenvironment.
Zhang MW, Fujiwara K, Che X, Zheng S, Zheng L. Zhang MW, et al. Among authors: zheng s, zheng l. J Zhejiang Univ Sci B. 2017 May;18(5):365-372. doi: 10.1631/jzus.B1600579. J Zhejiang Univ Sci B. 2017. PMID: 28471108 Free PMC article. Review.
Circulating Tumor DNA as a Clinical Test in Resected Pancreatic Cancer.
Groot VP, Mosier S, Javed AA, Teinor JA, Gemenetzis G, Ding D, Haley LM, Yu J, Burkhart RA, Hasanain A, Debeljak M, Kamiyama H, Narang A, Laheru DA, Zheng L, Lin MT, Gocke CD, Fishman EK, Hruban RH, Goggins MG, Molenaar IQ, Cameron JL, Weiss MJ, Velculescu VE, He J, Wolfgang CL, Eshleman JR. Groot VP, et al. Among authors: zheng l. Clin Cancer Res. 2019 Aug 15;25(16):4973-4984. doi: 10.1158/1078-0432.CCR-19-0197. Epub 2019 May 29. Clin Cancer Res. 2019. PMID: 31142500 Free PMC article.
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