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Page 1
Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases.
Nutma E, Fancy N, Weinert M, Tsartsalis S, Marzin MC, Muirhead RCJ, Falk I, Breur M, de Bruin J, Hollaus D, Pieterman R, Anink J, Story D, Chandran S, Tang J, Trolese MC, Saito T, Saido TC, Wiltshire KH, Beltran-Lobo P, Phillips A, Antel J, Healy L, Dorion MF, Galloway DA, Benoit RY, Amossé Q, Ceyzériat K, Badina AM, Kövari E, Bendotti C, Aronica E, Radulescu CI, Wong JH, Barron AM, Smith AM, Barnes SJ, Hampton DW, van der Valk P, Jacobson S, Howell OW, Baker D, Kipp M, Kaddatz H, Tournier BB, Millet P, Matthews PM, Moore CS, Amor S, Owen DR. Nutma E, et al. Among authors: muirhead rcj. Nat Commun. 2023 Aug 28;14(1):5247. doi: 10.1038/s41467-023-40937-z. Nat Commun. 2023. PMID: 37640701 Free PMC article.
Diverse human astrocyte and microglial transcriptional responses to Alzheimer's pathology.
Smith AM, Davey K, Tsartsalis S, Khozoie C, Fancy N, Tang SS, Liaptsi E, Weinert M, McGarry A, Muirhead RCJ, Gentleman S, Owen DR, Matthews PM. Smith AM, et al. Among authors: muirhead rcj. Acta Neuropathol. 2022 Jan;143(1):75-91. doi: 10.1007/s00401-021-02372-6. Epub 2021 Nov 12. Acta Neuropathol. 2022. PMID: 34767070 Free PMC article.
A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier function in Alzheimer's disease.
Tsartsalis S, Sleven H, Fancy N, Wessely F, Smith AM, Willumsen N, Cheung TKD, Rokicki MJ, Chau V, Ifie E, Khozoie C, Ansorge O, Yang X, Jenkyns MH, Davey K, McGarry A, Muirhead RCJ, Debette S, Jackson JS, Montagne A, Owen DR, Miners JS, Love S, Webber C, Cader MZ, Matthews PM. Tsartsalis S, et al. Among authors: muirhead rcj. Nat Commun. 2024 Mar 12;15(1):2243. doi: 10.1038/s41467-024-46630-z. Nat Commun. 2024. PMID: 38472200 Free PMC article.
Characterisation of premature cell senescence in Alzheimer's disease using single nuclear transcriptomics.
Fancy NN, Smith AM, Caramello A, Tsartsalis S, Davey K, Muirhead RCJ, McGarry A, Jenkyns MH, Schneegans E, Chau V, Thomas M, Boulger S, Cheung TKD, Adair E, Papageorgopoulou M, Willumsen N, Khozoie C, Gomez-Nicola D, Jackson JS, Matthews PM. Fancy NN, et al. Among authors: muirhead rcj. Acta Neuropathol. 2024 May 2;147(1):78. doi: 10.1007/s00401-024-02727-9. Acta Neuropathol. 2024. PMID: 38695952 Free PMC article.