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Page 1
Cellular Validation of a Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2.
Gan J, de Vries J, Akkermans JJLL, Mohammed Y, Tjokrodirijo RTN, de Ru AH, Kim RQ, Vargas DA, Pol V, Fasan R, van Veelen PA, Neefjes J, van Dam H, Ovaa H, Sapmaz A, Geurink PP. Gan J, et al. Among authors: akkermans jjll. ACS Chem Biol. 2023 Sep 15;18(9):2003-2013. doi: 10.1021/acschembio.3c00227. Epub 2023 Aug 29. ACS Chem Biol. 2023. PMID: 37642399 Free PMC article.
Chemical and genetic control of IFNγ-induced MHCII expression.
Wijdeven RH, van Luijn MM, Wierenga-Wolf AF, Akkermans JJ, van den Elsen PJ, Hintzen RQ, Neefjes J. Wijdeven RH, et al. EMBO Rep. 2018 Sep;19(9):e45553. doi: 10.15252/embr.201745553. Epub 2018 Jul 18. EMBO Rep. 2018. PMID: 30021835 Free PMC article.
USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism.
Gan J, Pinto-Fernández A, Flierman D, Akkermans JJLL, O'Brien DP, Greenwood H, Scott HC, Fritz G, Knobeloch KP, Neefjes J, van Dam H, Ovaa H, Ploegh HL, Kessler BM, Geurink PP, Sapmaz A. Gan J, et al. Among authors: akkermans jjll. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2315163120. doi: 10.1073/pnas.2315163120. Epub 2023 Dec 6. Proc Natl Acad Sci U S A. 2023. PMID: 38055744 Free PMC article.
The ORP9-ORP11 dimer promotes sphingomyelin synthesis.
Cabukusta B, Borst Pauwels S, Akkermans JJLL, Blomberg N, Mulder AA, Koning RI, Giera M, Neefjes J. Cabukusta B, et al. Among authors: akkermans jjll. Elife. 2024 Aug 6;12:RP91345. doi: 10.7554/eLife.91345. Elife. 2024. PMID: 39106189 Free PMC article.
Systems mapping of bidirectional endosomal transport through the crowded cell.
Jongsma MLM, Bakker N, Voortman LM, Koning RI, Bos E, Akkermans JJLL, Janssen L, Neefjes J. Jongsma MLM, et al. Among authors: akkermans jjll. Curr Biol. 2024 Oct 7;34(19):4476-4494.e11. doi: 10.1016/j.cub.2024.08.026. Epub 2024 Sep 13. Curr Biol. 2024. PMID: 39276769 Free PMC article.
Multi-omics analyses of cancer-linked clinical salmonellae reveal bacterial-induced host metabolic shift and mTOR-dependent cell transformation.
Stévenin V, Coipan CE, Duijster JW, van Elsland DM, Voogd L, Bigey L, van Hoek AHAM, Wijnands LM, Janssen L, Akkermans JJLL, Neefjes-Borst A, Franz E, Mughini-Gras L, Neefjes J. Stévenin V, et al. Among authors: akkermans jjll. Cell Rep. 2024 Nov 26;43(11):114931. doi: 10.1016/j.celrep.2024.114931. Epub 2024 Nov 2. Cell Rep. 2024. PMID: 39488829 Free article.
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