Mahnashi MH - Search Results

1

Pharmacological evaluations of amide carboxylates as potential anti-Alzheimer agents: anti-radicals, enzyme inhibition, simulation and behavioral studies in animal models.

Mahnashi MH, Ali S, M Alshehri O, Almazni IA, Asiri SA, Sadiq A, Zafar R, Jan MS. Mahnashi MH, et al. J Biomol Struct Dyn. 2024 Oct;42(17):9249-9268. doi: 10.1080/07391102.2023.2251052. Epub 2023 Aug 29. J Biomol Struct Dyn. 2024. PMID: 37642974

2

Synthesis, pharmacological evaluation and Molecular modelling studies of pregnenolone derivatives as inhibitors of human dihydrofolate reductase.

Bilal Tufail M, Aamir Javed M, Ikram M, Mahnashi MH, Alyami BA, Alqahtani YS, Sadiq A, Rashid U. Bilal Tufail M, et al. Among authors: mahnashi mh. Steroids. 2021 Apr;168:108801. doi: 10.1016/j.steroids.2021.108801. Epub 2021 Feb 5. Steroids. 2021. PMID: 33549543

3

Phytochemical profiling of bioactive compounds, anti-inflammatory and analgesic potentials of Habenaria digitata Lindl.: Molecular docking based synergistic effect of the identified compounds.

Mahnashi MH, Alyami BA, Alqahtani YS, Jan MS, Rashid U, Sadiq A, Alqarni AO. Mahnashi MH, et al. J Ethnopharmacol. 2021 Jun 12;273:113976. doi: 10.1016/j.jep.2021.113976. Epub 2021 Feb 27. J Ethnopharmacol. 2021. PMID: 33647424

4

Synthesis of Michael Adducts as Key Building Blocks for Potential Analgesic Drugs: In vitro, in vivo and in silico Explorations.

Ahmad S, Mahnashi MH, Alyami BA, Alqahtani YS, Ullah F, Ayaz M, Tariq M, Sadiq A, Rashid U. Ahmad S, et al. Among authors: mahnashi mh. Drug Des Devel Ther. 2021 Mar 23;15:1299-1313. doi: 10.2147/DDDT.S292826. eCollection 2021. Drug Des Devel Ther. 2021. PMID: 33790541 Free PMC article.

5

Tailoring the substitution pattern of Pyrrolidine-2,5-dione for discovery of new structural template for dual COX/LOX inhibition.

Sadiq A, Mahnashi MH, Alyami BA, Alqahtani YS, Alqarni AO, Rashid U. Sadiq A, et al. Among authors: mahnashi mh. Bioorg Chem. 2021 Jul;112:104969. doi: 10.1016/j.bioorg.2021.104969. Epub 2021 May 7. Bioorg Chem. 2021. PMID: 34023639

6

Venlafaxine demonstrated anti-arthritic activity possibly through down regulation of TNF-α, IL-6, IL-1β, and COX-2.

Mahnashi MH, Jabbar Z, Alamgeer, Irfan HM, Asim MH, Akram M, Saif A, Alshahrani MA, Alshehri MA, Asiri SA. Mahnashi MH, et al. Inflammopharmacology. 2021 Oct;29(5):1413-1425. doi: 10.1007/s10787-021-00849-0. Epub 2021 Jul 24. Inflammopharmacology. 2021. PMID: 34302591

7

Cytotoxicity, anti-angiogenic, anti-tumor and molecular docking studies on phytochemicals isolated from Polygonum hydropiper L.

Mahnashi MH, Alqahtani YS, Alyami BA, Alqarni AO, Ullah F, Wadood A, Sadiq A, Shareef A, Ayaz M. Mahnashi MH, et al. BMC Complement Med Ther. 2021 Sep 24;21(1):239. doi: 10.1186/s12906-021-03411-1. BMC Complement Med Ther. 2021. PMID: 34560864 Free PMC article.

8

Neuroprotective potentials of selected natural edible oils using enzyme inhibitory, kinetic and simulation approaches.

Mahnashi MH, Alyami BA, Alqahtani YS, Alqarni AO, Jan MS, Ayaz M, Ullah F, Shahid M, Rashid U, Sadiq A. Mahnashi MH, et al. BMC Complement Med Ther. 2021 Oct 2;21(1):248. doi: 10.1186/s12906-021-03420-0. BMC Complement Med Ther. 2021. PMID: 34600509 Free PMC article.

9

Structural Modification, In Vitro, In Vivo, Ex Vivo, and In Silico Exploration of Pyrimidine and Pyrrolidine Cores for Targeting Enzymes Associated with Neuroinflammation and Cholinergic Deficit in Alzheimer's Disease.

Javed MA, Ashraf N, Saeed Jan M, Mahnashi MH, Alqahtani YS, Alyami BA, Alqarni AO, Asiri YI, Ikram M, Sadiq A, Rashid U. Javed MA, et al. Among authors: mahnashi mh. ACS Chem Neurosci. 2021 Nov 3;12(21):4123-4143. doi: 10.1021/acschemneuro.1c00507. Epub 2021 Oct 13. ACS Chem Neurosci. 2021. PMID: 34643082

10

Crude extract and isolated bioactive compounds from Notholirion thomsonianum (Royale) Stapf as multitargets antidiabetic agents: in-vitro and molecular docking approaches.

Mahnashi MH, Alqahtani YS, Alqarni AO, Alyami BA, Jan MS, Ayaz M, Ullah F, Rashid U, Sadiq A. Mahnashi MH, et al. BMC Complement Med Ther. 2021 Oct 27;21(1):270. doi: 10.1186/s12906-021-03443-7. BMC Complement Med Ther. 2021. PMID: 34706708 Free PMC article.

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