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Page 1
Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells.
Krawczynska N, Wang Y, Lim K, Das Gupta A, Lenczowski A, Abughazaleh M, Bendre SV, Kockaya LI, Schane CP, Fei Y, Hernandez AG, Drnevich J, Chan J, Dobrucki LW, Boppart MD, Ostrander J, Nelson ER. Krawczynska N, et al. Among authors: schane cp. bioRxiv [Preprint]. 2024 Aug 2:2024.08.02.606061. doi: 10.1101/2024.08.02.606061. bioRxiv. 2024. PMID: 39131340 Free PMC article. Preprint.
Development of NR0B2 as a therapeutic target for the re-education of tumor associated myeloid cells.
Vidana Gamage HE, Albright ST, Smith AJ, Farmer R, Shahoei SH, Wang Y, Fink EC, Jacquin E, Weisser E, Bautista RO, Henn MA, Schane CP, Nelczyk AT, Ma L, Das Gupta A, Bendre SV, Nguyen T, Tiwari S, Krawczynska N, He S, Tjoanda E, Chen H, Sverdlov M, Gann PH, Boidot R, Vegran F, Fanning SW, Apetoh L, Hergenrother PJ, Nelson ER. Vidana Gamage HE, et al. Among authors: schane cp. Cancer Lett. 2024 Aug 10;597:217086. doi: 10.1016/j.canlet.2024.217086. Epub 2024 Jun 27. Cancer Lett. 2024. PMID: 38944231 Free article.
NR0B2 re-educates myeloid immune cells to reduce regulatory T cell expansion and progression of breast and other solid tumors.
Vidana Gamage HE, Shahoei SH, Wang Y, Jacquin E, Weisser E, Bautista RO, Henn MA, Schane CP, Nelczyk AT, Ma L, Das Gupta A, Bendre SV, Nguyen T, Tiwari S, Tjoanda E, Krawczynska N, He S, Albright ST, Farmer R, Smith AJ, Fink EC, Chen H, Sverdlov M, Gann PH, Boidot R, Vegran F, Fanning SW, Hergenrother PJ, Apetoh L, Nelson ER. Vidana Gamage HE, et al. Among authors: schane cp. Cancer Lett. 2024 Aug 10;597:217042. doi: 10.1016/j.canlet.2024.217042. Epub 2024 Jun 20. Cancer Lett. 2024. PMID: 38908543 Free article.
The combination of PAC-1 and entrectinib for the treatment of metastatic uveal melanoma.
Boudreau MW, Tonogai EJ, Schane CP, Xi MX, Fischer JH, Vijayakumar J, Ji Y, Tarasow TM, Fan TM, Hergenrother PJ, Dudek AZ. Boudreau MW, et al. Among authors: schane cp. Melanoma Res. 2023 Dec 1;33(6):514-524. doi: 10.1097/CMR.0000000000000927. Epub 2023 Sep 22. Melanoma Res. 2023. PMID: 37738028 Free PMC article. Clinical Trial.
Re-education of myeloid immune cells to reduce regulatory T cell expansion and impede breast cancer progression.
Gamage HEV, Shahoei SH, Albright ST, Wang Y, Smith AJ, Farmer R, Fink EC, Jacquin E, Weisser E, Bautista RO, Henn MA, Schane CP, Nelczyk AT, Ma L, Gupta AD, Bendre SV, Nguyen T, Tiwari S, Krawczynska N, He S, Tjoanda E, Chen H, Sverdlov M, Gann PH, Boidot R, Vegran F, Fanning SW, Apetoh L, Hergenrother PJ, Nelson ER. Gamage HEV, et al. Among authors: schane cp. bioRxiv [Preprint]. 2023 Aug 14:2023.08.14.553229. doi: 10.1101/2023.08.14.553229. bioRxiv. 2023. PMID: 37645737 Free PMC article. Preprint.
Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model.
Ranoa DRE, Sharma P, Schane CP, Lewis AN, Valdez E, Marada VVVR, Hager MV, Montgomery W, Wolf SP, Schreiber K, Schreiber H, Bailey K, Fan TM, Hergenrother PJ, Roy EJ, Kranz DM. Ranoa DRE, et al. Among authors: schane cp. J Immunother Cancer. 2023 May;11(5):e006509. doi: 10.1136/jitc-2022-006509. J Immunother Cancer. 2023. PMID: 37258040 Free PMC article.
Synergistic Combination of Oncolytic Virotherapy and Immunotherapy for Glioma.
Tang B, Guo ZS, Bartlett DL, Yan DZ, Schane CP, Thomas DL, Liu J, McFadden G, Shisler JL, Roy EJ. Tang B, et al. Among authors: schane cp. Clin Cancer Res. 2020 May 1;26(9):2216-2230. doi: 10.1158/1078-0432.CCR-18-3626. Epub 2020 Feb 4. Clin Cancer Res. 2020. PMID: 32019860 Free PMC article.